慢性阻塞性肺疾病急性加重患者在院期间红细胞分布宽度与预后相关性研究

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udyon theCorrelation BetweenRed Blood Cell Distribution WidthandPrognosis inPatients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease During Hospitalization

WANGYuan1，XINCaixia1，YANGHaiying1，CHENDan2，HUANGNa3 （1.DepartmentofespratoryndCriticalCare edicine，enshouCountyeople'sHspital，Renshou6Ooo，ca，in； 2.Respiratory Department of Yunchang Hospital in Renshou County，Renshou 62o5oo，Sichuan，China； 3.DepartmentofRespiratoryandCritical Care Medicine，theFirst Afiliated Hospital of Chengdu Medical College， Chengdu ，Sichuan， China）

Abstract：ObeixplooelolodcellstioDndogosofcuaceb obstructivepulmoarydseaseECOpatintsrigospitalizoMetodsTcaldtaofECOpatintsdmitedttesie careunitfromJanuary208toDecember2O19wereextractedfromtheMMC-IVpublicdatabase.Accordingtothelevelofredblodcel distribution width，they were divided into high RDW group （ R D W>1 5 % ）and normal RDW group （ R D W？ 1 5 % ）.The general conditions of AECOPD patientsintetoousreomparedKaplaneieretdsedtodrateurvivaluretoompareefreceofyeariale betweenthetwogroups.ROCcurvewasusedtoevaluatethediagnosticvalueofRDWinthedeathofAECOPDpatientswithin1year.Cox proportionalhadegressoaalysasdtaltsfctocigtathfCOpatintsResultsotalof patientswereicludedCompeditheoalDoup，tepropoiofpertesioabetesartfurendSOFsoeig RDWgroup were higher than thosein the normal RDW group（ .The1-yearmortalityof patientsinthehighRDWgroup（80.57 % ）washigher than that in the normal RDW group （ 7 1 . 0 9 % ） ，P=0.007）.The results of ROC curve showed that the area under the curve of RDW predicting thedeathfACOtisinaras85%.2）tsivi7esefitndf valuewas 1 5 . 8 % .TheresultsofCoxproportionalhazardregressionanalysisshowedthatRDWwasanindependentriskfactorforpredictingthedeath fAECOPDpts（76.543）CcueasefDedepdtsfct prognosis of patients with AECOPD，which can beused to judge the risk of death in patients with AECOPD.

Keywords：MIMIC-IV database；Red blood cell distributionwidth；AECOPD；Prognosis

慢性阻塞性肺疾病急性加重（acuteexacerbationof chronic obstructive pulmonary disease，AECOPD）是导致COPD患者住院治疗的主要原因，且与患者预后不良有关。（剩余8480字）