桃红四物汤特征图谱及多成分含量研究

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关键词经典名方；桃红四物汤；特征图谱；多中图分类号R286 文献标识码A文章编号 0517-6611（2025）13-0170-04d . issn. 0517-6611.2025.13. 032开放科学（资源服务）标识码（OSID）：

Study on the Characteristic Chromatogram and Determination of Multi-component Content of Taohong Siwu Decoction ZHU Qi-liang，ZHOU Quan²，CAOLan-lan²etal（1.GuangzhouBaiyunshanzhongyiPharmaceuticalCo.，Ld.，Guangzhou，Guangdong 510530;2.Shanghai R&D Center for Standardization of Chinese Medicines，Shanghai ）

AbstractObectiveTostablishamethodforcharacteristicromatoamanddetermiatioofulticompoentsofTaohongSiDeco tion.[Method]CAPCELL PAK C18 （MGII） column（ 250nm×4.6nm，5μm） ）was used and the mobile-phase was methanol-acetonitrile -0.2% phosphoric acid solution with gradient elution. The column temperature was 30qC . The detection wavelengths were 280，210，230，330 and 403 nm. The flow rate was 1.0mL/min and the injection volume was 20μL . The similarity evaluation combined with cluster analysis was used toevaluateteharacteristicapof5batsofaohongSiuDecoctioandteotentsof1omponntsredeteindiulta ously.Resultesilarityfebcharkcharacteristcspectraof15batchsofTohongSiuDecoctionasgeaterthanO.9and16 commonpeakswerealibratedandatotalof13hromatographicpeakswereidentifed.The1omponentssowedgodlinearelatiosis within a certain concentration range （ ）.[Conclusion]The established method for characteristic chromatogram and content determinationofmultcomponntsofTaohongSiuDecoctionereacurateandreliable，hichanprovidareferenceforfurtqualityotol valuation of traditional classical formula.

KeywordTraditioalclasicfoula;TaongSiDecotion;Characteritichoatoga;Multi-opoents;Contentdeteatio

桃红四物汤出自清朝柴得华所撰妇科名著《妇科冰鉴》，该方由当归、地黄、川芎、白芍、桃仁、红花6味药组成[1]。（剩余5224字）