不同年龄段食蟹猴血生化指标检测及相关性分析

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关键词食蟹猴；血液生化指标；年龄段;相关性中图分类号Q95-33文献标识码A文章编号 0517-6611（2025）13-0071-04doi：10.3969/j.issn.0517-6611. 2025. 13. 014

开放科学（资源服务）标识码（OSID）：

Detection and Correlation Analysis of Blood Biochemical Across Different Age Groups of Cynomolgus Monkeys PANXi-ying1，ZHANG Pengfei，SHENGuoetal（1.Guangxi HuarenJiying BiotechnologyCo.，Ld.，Naning，Guangxi500; 2.Guangxi Academy of Sciences，Nanning，Guangxi 530007）

AbstractObective]Tostudythebloodbiochemicalofcynomogusmonkeysatdiferentagegroupsndivestigatetherelatioshpbetweenthetwovariables.Method]Atotalof196malecynomolgusmonkeys were selectedanddividedinto5groups：juvenilegroup（1-4 yearsold），younggroup（5-8yearsold），midle-agegroup（9-12yearsold），oldgroup（13-16yearsold）andveryoldgroup（17-20 yearsold）19lodceicalparameterseredetectedompasosereadeaongdierentagegoupsndthelatioieteen each parameterandagewasanalyzed.Result]HBAlc，FBGandTGincreasedwithageandwere positivelycorelatedwithage.BUNand CREwerenegatielycelatedwithagefromjuenile toyoung，andpositvelyorrlatedwithagefromyoungtveryoldCHL，LDL-C， HDL-C，ALB，，ASGG，ALP，Caandwrenegtivelyoelated withgfrojuveniletomdlegendpositivelyae withagefromdlaeteryold，ndCKweegativeloeadijueilyoungndosiee tedwithagefromyoungtoveryold.Conclusion]isstudyprovidedareferencebasisforteapplicationofcyomolgusmokeysfeld of biomedicine.

Key WordsCynomolgus monkeys;Blood biochemical; Age group;Correlation

动物实验在人类疾病机理研究和新药研发过程中是不可缺少的一部分，非人灵长类实验动物与人类的遗传物质具有 57.0%～98.5% 的同源性，是新药研发临床前最理想的实验动物。（剩余6252字）