基于数据挖掘探讨中医药治疗老年性白内障术后干眼症用药规律

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[关键词]干眼症;老年性白内障;术后;中医药;文献;数据挖掘;用药规律 [中图分类号]R276.7 [文献标志码]A [文章编号]0256-7415(2025)11-0001-06 DOl:10.13457/j.cnki.jncm.2025.11.001
Exploration on Medication Rules of Chinese Medicine in the Treatment of Xerophthalmia After Operation for Senile Cataract Based on Data Mining Techniques
HUFangxin¹,XU Siting1,YUAN Yuan²,WANG Yan³ 1.TheSecond Clinical Medical Schoolof Guangzhou UniversityofChinese Medicine,Guangzhou Guangdong 51006,China; 2.Guangdong Provincial Hospitalof ChineseMedicine,GuangzhouGuangdong 51O120,China;3.Guangdong SecondTraditional Chinese Medicine Hospital,Guangzhou Guangdong 51Oo95,China
Abstract:Objective:To explore the medication rules of Chinese Medicine in the treatment of xerophthalmia after operation for senilecataract based on Traditional Chinese Medicine Inheritance Computing System(TCMICS)V3.5. Methods:Prescriptions for the treatment of xerophthalmia after operation for senile cataract were retrieved fromthe China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform(Wanfang),and China Science and Technology Journal Database(VIP)from the establishment of the databases up to October 31,2024.The TCMICSV3.5 was used to analyze the frequency of medication use,naturesand flavors,channel entry,association rules,and clustering.Results:A total of 198 prescriptions involving 243 diferent Chinese medicines were included. High-frequency Chinesemedicines included Chrysanthemi Flos,Angelicae Sinensis Radix,Poria,Glycyrhizae Radix etRhizoma,and Rehmanniae Radix.The medicinal natures were mainly cold and warm,with flavors primarily sweet,biter,and pungent.The channel entries were mainly liver,lung,and spleen meridians.Clustering analysis identified five groups of herb combinations.Conclusion:Chinese medicine treatment for xerophthalmia afteroperation forsenilecataract primarily focuseson nourishing the liver and kidneys,clearing heat and improving vision,regulating qiand invigorating blood,and strengthening the spleenand draining dampness.The main herbalcompositions are Danggui Shaoyao Powderand Qiju Dihuang Pils.Thissuggests that themain pathogenesisof xerophthalmiaafter operationforsenilecataract involves wind-heat inthe liverandlung withdampnessaffecting theeyes,andqi stagnation with blood stasis.
Keywords:Xerophthalmia;Senile cataract;After operation;Chinese medicine;Literature;Data mining; Medication rules
老年性白内障以外科手术为主,但术后常伴有干眼症发生或加重,对患者的手术效果和生活质量产生极大影响,阻碍患者的康复预后。(剩余6844字)