铁代谢异常对代谢相关脂肪性肝病的影响及治疗研究进展

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【中图分类号】R575.5 【文献标志码】A

【Abstractron，hichsteghetontentandistemosrequredtaceelementintemanodyisitaltoteolab lismandlifeactivitiesofourbody.Theliveristhemainstorageorganofiron，ndironmetabolismdisordershavevarousharstothe liverandareassociatedwiththedevelomentandprogesionofvaretyofiverdiseass.Inrecentyars，metabolicassociatedfatt liverdiseasehaseomealiverdiseasewithaighincdenerateglobalyanditsevelopmentandprogessonareafecedbyany factorssuchasironmetabolismandinvolvesdiferentmolecularmechanisms.Thisaticlereviewstheefectofironmetabolisdisor dersonmetabolicassiatedfattyliverdiseaseadsummarizeste treatmentmethdsformetabolicassociatedfatyliverdiseasebasd onironmetabolismdisodesindertopovidemoreideasforthepreventioandreatmentofmetabolicsiatedfattyliveisease. 【Key words]iron metabolism;iron overload;ferroptosis;metabolic associated fatty liver disease

铁是人体内必不可少的微量元素，其正常代谢在维持人体健康中有至关重要的作用，而其代谢异常也从多方面影响疾病的发生发展。（剩余15559字）