肺动脉高压患者随访及CT定量监测的评估价值研究

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Astudy of the relationship between CTparameters of pulmonarysmall vessel parametersand the

prognosisof patientswith pulmonary hypertension

CaiLeilei

DepartmentofRadiology，BaofengBranch，theSecondPeople'sHospitalofPingdingshanCity，Pingdingshan 467400， China

【Abstract】Objective To investigate the relationship between CT parameters of pulmonary small vessels and prognosis of patients with pulmonary hypertension.MethodsCT scan data of 68 patients with pulmonary hypertension treated inourhospitalfrom January 2020 to December2O22 were retrospectivelyanalyzed.Allpatients were followed up for one year，and were divided into good prognosis group （ n =39 cases） and poor prognosis group （ n= 29）according to follow-up outcomes. CT parameters of pulmonary small vessels were compared two weeks after admission.Multivariate regression was used to analyze the correlation between CT pulmonary small vessel parameters and the prognosis of patients with pulmonary hypertension，and receiver operating characteristic curve （ROC curve） wasused to analyze the clinical value of CT pulmonary small vessel parameters in predicting the prognosis of patients with pulmonary hypertension. ResultsThe CSA and % CSA5-10 in the poor prognosis group were lower than those in the good prognosis group [CSA：（5.6±1.5）mm² vs.（7.1±1.6）mm² ; τ =3.830， P<0.001 % CSA5- 10： （41.8±7.3）% vs.（61.3±11.2） % t=8.663 P<0.001 ]， the % CSA<5 in the poor prognosis group was higher than that in the good prognosis group [CSA：（59.5±5.8）% vs. （47.2±9.9）%; t= -6.451， P <0.001]. Multiple regression analysis found that CSA[OR（95%CI）=0.457（0.307 ，0.680），P<0.001]， % CSA5-10[0R（95%CI） ≡= 0.498（0.253，0.980）， P< 0.001] and 095）， P <0.001] were correlated with the prognosis of patients with pulmonary hypertension. ROC curve analysis showed that %CSAS-10 had good clinical value in predicting the prognosis of patients with pulmonary hypertension [AUC（95%C1）=0.924（0.833，0.974），P<0.001]. ConclusionCT parameters of pulmonary small vessels have a certaincorelation with the prognosis of patients with pulmonary hypertension，and can provide an efective objective basis for clinical prediction of patient prognosis.

【Key words】Pulmonary hypertension； CT; Small pulmonary vessels；Prognosis；Correlation；Predictivevalue

DOI：10.19522/j.cnki.1671-5098.2025.01.009

肺动脉高压是一种由多种异源性疾病和不同发病机制引起的临床综合征，主要病理特征是肺血管结构或功能改变，可导致肺动脉压力升高，并且随着病程的发展，肺血管阻力会逐渐增大，诱发右心衰竭甚，加大患者死亡风险[1-2]。（剩余7783字）