淋巴管超声造影与静脉超声造影在鉴别诊断甲状腺癌颈部转移淋巴结中的应用

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中图分类号：R44.451 文献标识码：A 文章编号：1000-503X（2025）01-0016-07

DOI：10.3881/j.issn.1000-503X.16120

Lymphatic and Venous Contrast-Enhanced Ultrasound Imaging for Differential Diagnosis of Cervical Lymph Node Metastasis in Thyroid Cancer

LI Xu，WAN Wenbo，GAO Tian，GOU Taohua，ZHANG Yan

Department of Ultrasound，The First Medical Center，Chinese PLA General Hospital，Beijing 100853，China

Corresponding author：ZHANG Yan Tel：010-66935241，E-mail：zhangyaner301@126.com

ABSTRACT： ObjectiveTo investigate the value of the novel lymphatic contrast- enhanced ultrasound （LCEUS）and conventional venous contrast-enhancedultrasound（VCEUS）in the diferential diagnosisof benign and malignant cervical lymph nodes in patients with thyroid cancer.MethodsPatients with suspected thyroid cancer underwent conventional ultrasound，VCEUS，and LCEUS examinations of cervical lymph nodes before biopsy.The diagnosticabilities of conventional ultrasound，VCEUS，and LCEUS were compared with pathological results as the golden standard. ResultsForty-four patients with 52 lymph nodes were included in the final data.Thirty-eight metastatic lymph nodes were confirmed bypathological results，and14 were benign.The diagnostic sensitivity，specificity，and accuracy were 97.37% ， 71.43% ，and 90.38% for LCEUS， 92.11% ， （20 35.71% ，and 76.92% for VCEUS，and 94.74% ， 21.43% ，and 75.00% for conventional ultrasound， respectively.The area under the curve of LCEUS analyzed bythe receiver operating characteristic curve was greaterthanthatofVCEUS（ P=0.020 ）and conventional ultrasound（ P<0.001 ）.ConclusionLCEUS could significantly improvethe diferential diagnosis of cervical lymph node metastasis in the patients with thyroid cancer，providing a basis for precise clinical treatment.

Key words：thyroid；ultrasound；contrast-enhanced ultrasound imaging；lymph node

ActaAcadMedSin，2025，47（1）：16-22

甲状腺癌发病率居高不下，已引发全球关注，尽管大多数病例为预后较好的乳头状癌，但仍有 60% ＼～70% 的机率发生颈部淋巴结转移[1]。（剩余11031字）