中医药治疗儿童变应性鼻炎的临床治则治法及作用机制研究进展

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中图分类号R285；R965 文献标志码A 文章编号 1001-0408（2025）22-2879-06

DOI 10.6039/j.issn.1001-0408.2025.22.22

ABSTRACTAlergicrhinitis（AR）isoneof themostcommon chronicnon-infectious inflammatorydiseasesinchildren. Traditional Chinesemedicine（TCM）employsacomprehensivetherapeuticsystem integrating treatment bystagesandsyndrome diferentitionandtreatment，demonstratingsignificantadvantagesinthemanagementofpediatricAR.Tisarticlesystematicaly reviewstheclinicaltreatmentmethodsandunderlyingmechanismsofTCMforpediatricARinrecentyears.Itisfoundthatinternal therapies（suchasherbal formulasor Chinesepatent medicines likeXiaoqinglong decoction，Yiqi tuomindecoction），external therapies（includingintradermalnedles，cupointaplication，tuina，anderbalnasaltherapy），aswellascombiedintealand exteralaproaches（oralerbscombinedwithacupointapplication），avedmonstratedsignificanteffectsinaleviatingclinical symptoms，improving immune indicators，andreducingrecurencerates inchildren withAR.Theunderlying mechanismsare primarilyasocatedwiththeregulationofsignalingpathwayssuchasTl-likreceptor/uclearfactor-kappaBandmitogen-activated protein kinase，therebymodulating immune balance，suppressing inflammatoryresponses，inhibitingpyroptosis，reducingmucus secretion，and promoting nasal mucosal repair.

KEYWORDSalergicrhinitis；traditionalChinesemedicine；treatmentbystages；syndromediferentiationandtreatment; mechanism of action

变应性鼻炎（allergicrhinitis，AR），即过敏性鼻炎，是一种由免疫球蛋白E（immunoglobulinE，IgE）介导的鼻黏膜慢性非感染性炎症疾病，典型症状包括鼻塞、鼻痒、喷嚏及清水样鼻涕[]。（剩余11971字）