COPD病人睡眠障碍发生率及其影响因素的Meta分析
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The incidence and influencing factors of sleep disorders in COPD patients：a Meta-analysis
ZHANG Man，YUN Jie，LUO Mingxia，WU Tingting，MAO Yuting，HE Qinrui，CHENG ChunfangSchool of Nursing，Chengdu University of Traditional Chinese Medicine，Sichuan 610075 ChinaCorresponding Author YUN Jie，E-mail：836762774@qq.com
Abstract Objective：To systematically evaluate the influencing factors of sleep disorders in patients with chronic obstructive pulmonary disease（COPD），and provide a basis for early identification and intervention of sleep deprivation and improvement of patient coping ability.Methods：Retrieved relevant literature on the influencing factors of sleep disorders in COPD patients from CNKI，WanFang Database，VIP database，CBM，PubMed，EMbase，Web of Science，and the Cochrane Library.The retrieval time was from the inception to May 4，2023.Results：A total of 13 articles were included，and the incidence of sleep disorders was 52%.Among them，the respiratory distress index（mMRC） was≥2 points（OR=2.01，95%CI 1.14-3.53，P<0.05），the self-evaluation test（CAT） of COPD patients was≥10 points（OR=1.24，95%CI 1.01-1.53，P<0.05），the pulmonary function assessment（GOLD） was graded as grade Ⅲ-Ⅳ（OR=2.76，95%CI 1.64-4.65，P<0.05），and the comorbid obstructive sleep apnea hypopnea syndrome（OSA）（OR=2.12，95%CI 1.64-2.74，P<0.05），fatigue（OR=4.56，95%CI 2.47-8.43，P<0.05），anxiety（OR=1.13，95%CI 1.07-1.18，P<0.05），depression（OR=1.25，95%CI 1.09-1.45，P<0.05），and long-term bed rest（OR=2.18，95%CI 1.43-3.32，P<0.05） were the main influencing factors of sleep disorders in COPD patients.Conclusion：Current evidence suggests that COPD patients have a higher incidence of sleep disorders，with mMRC≥2，CAT≥10，GOLD grades Ⅲ-Ⅳ，comorbidities with OSA，fatigue，anxiety，depression，and long-term bed rest being the main influencing factors for sleep disorders in COPD patients.
Keywords chronic obstructive pulmonary disease，COPD;sleep disorders;influencing factors;Meta-analysis;evidence-based nursing
摘要 目的：系统评价慢性阻塞性肺疾病（COPD）病人睡眠障碍的影响因素，为早期识别和干预病人睡眠剥夺、提高病人应对能力提供依据。（剩余12038字）