雷公藤多苷药理毒理作用研究进展

  • 打印
  • 收藏
收藏成功

【摘要】雷公藤多苷(TWP)是一种有效的抗炎免疫脂溶性混合物,广泛用于肾病、关节疾病的临床治疗,治疗效果好,但存在药物不良反应问题,如何科学有效地使用该药物成为临床应用面临的主要问题。本研究通过综合分析相关研究文献,探讨TWP药理毒理作用进展,以期为临床药物使用提供参考信息。

【关键词】雷公藤多苷;药理作用;毒理作用

【DOI编码】10.3969/j.issn.1674-4977.2023.04.030

Research Progress in Pharmacological and Toxicological Effects of Tripterygium Wilfordii Glycosides

LI Yan, REN Chao, ZOU Yang, PENG Huajun, QI Jun, YUAN Hongbo

(1. Hunan Qianjin Xieli Pharmaceutical Co., Ltd., Zhuzhou 412007, China; 2. Zhuzhou Qianjin Pharmaceutical Co., Ltd., Zhuzhou 412000, China)

Abstract: Tripterygium wilfordii polyglycoside (TWP) is an effective anti-inflammatory immune fat soluble mixture, which is widely used in the clinical treatment of kidney disease and joint disease. The treatment effect is good, but there are Adverse drug reaction. How to use the drug scientifically and effectively has become a major problem in clinical application. This study aims to comprehensively analyze relevant research literature and explore the progress in the pharmacological and toxicological effects of TWP, in order to provide reference information for clinical drug use.

Key words: tripterygium glycosides; pharmacological effects; toxicological effects

雷公藤多苷提取自雷公藤,雷公藤是木质藤本植物,在中药应用中被认为具有清热解毒、活血化瘀的作用,该药物最早见于《神农本草经》,书中记载其具有治疗膨胀、痞积、水肿及鱼口便毒、疟疾久不愈等效用。(剩余4536字)

目录
monitor