响应面法优化金银花中有机酸类成分提取工艺

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中图分类号：R284.2 文献标志码：A文章编号：1002-4026（2025）04-0001-07开放科学（资源服务）标志码（OSID）

Abstract ：Theextractionrateof organicacid components was usedasanindicator to investigatethe efects of extraction processparameters，namely，extractiontemperature，extractiontime，solid-liquidratio，and particlesizeontheextraction results using the water extraction method.A response surface model was established using a Box-Behnken design to optimizetheextraction processparameters fororganic acid components fromLonicerajaponicaThunb.with temperature， time，and solid-liquid ratioas factors.Results show that the optimal extraction process for organicacid components from Lonicera japonica Thunb. comprise an extraction temperature of 72∘C ， an extraction time of 90min ，and a solid-liquid ratio of 1 9：40mL .Under these conditions，the extraction rate of organic acid components can reach 5.16% with a relative error of 0.96% compared to the theoretical value.

Key words σ：σ Lonicera japonica Thunb.；organic acids；extraction；the response surface methodology

金银花（Lonicera japonica Thunb.）为忍冬科植物忍冬的干燥花蕾或待初开的花。（剩余5714字）