吩噻嗪基亚硫酸氢根荧光探针及其在食品和体内成像中的应用

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关键词：荧光探针；亚硫酸氢根；智能手机；食品样本；生物成像中图分类号：0482.31 文献标识码：ADOI：10.37188/CJL.20250180 CSTR：32170.14.CJL.20250180

Abstract：Excessive emissions of SO and its derivatives will cause serious harm to human health and the environment.Therefore，detecting HSOinfoodandenvironment iscrucialforsafeguardingpublic healthandenvironmental safety.In this paper，a red-emission-enhanced fluorescent probe（FSQ2）for HSO 13 was synthesized. The aldehyde group in FSQ2 undergoes a nucleophilic addition reaction with HSO ⋅3 ，resulting in significant fluorescence enhancement.FSQ2 exhibited excellnt performance，includingalarge Stokes shift（212nm），highselectivity，and superior sensitivity （LOD=2.52 μmol·L-1 ）.The quantitative analysis of HSO in food samples was successfully achieved by FSQ2.Meanwhile，smartphone-asisted FSQ2-based test strips were developed foron-site quantitativedetectionof HSO in watersamples.Most significantly，FSQ2 was successullyapplied for in vivo fluorescence imaging of HSO.

Key words：fluorescent probe;bisulfite；smartphone;food samples；bioimaging

1引言

二氧化硫（ SO2 是一种具有强烈刺激性气味的有毒气体[-2]，， SO2 及衍生物的过量排放对人体健康和自然环境将会造成严重危害3。（剩余12720字）