SGLT2i对脂蛋白代谢作用及临床意义的讨论

Discussion of the Effects of SGLT2i on Lipoprotein Metabolism and Clinical Implications

LI Meng，ZHOU Yaqi，FU Zhenyan

（Department of Coronary HeartDiseaseI，Heart Center，The First Afliated Hospital of Xinjiang Medical University，

Urumqi 830054，Xinjiang，China）

【Abstract】odumglucosecotransorter2ibitor（Si）ovelhypoglymicgentsaveatractedaetfortibilityto reducetheicideneofajordesecadovasularventsmproeraloutcosndduceteiskofartfilureospitalatioad death.HweverSGLTidootbenefitallcardiovascularevents，foreample，teirfectontheincidencofmyocardialinfarctiointhe overallpopaonsotsignifantorddyaveaneonsrokeisk.AninteresighyotesisistatSGayvealid abilitytouencecardiovasulardiseaseskfactorsarticularlywithegardtoheirfctsonlipdmetabolismlthoughtheisil controversyregdingteectsofionplasalipids，tevstmjoritfudsaveshowanicraseinotalholestolodensitylipopteolestoldsilptlstoldasergesdistatio Therefore，basedonrelevantstudies，thisarticlemainlydscusestheefectsofSLTionlipidmtabolismindabeticpatientsandteir potential clinical implications.

【Keywords】 Diabetes mellitus;Sodium-glucose cotransporter2 inhibitor;Plasma lipid

动脉粥样硬化性心血管疾病（atheroscleroticcardiovasculardisease，ASCVD）是糖尿病患者发病和死亡的主要原因，同时也是治疗成本的主要来源[1]。（剩余12218字）