急性上呼吸道感染与其他发热疾病患者外周血白细胞及相关炎症指标特征分析

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LinFangmi'，HuangJian²，ChenHuojil 'DepartmentofClinicalLaboratory，ShaxianDistrictGeneral HospitalofSanmingCitySanming365o5o，China; 2DepartmentoflinicalLaboratory，the90othHospitalofJointLgistics SupportForce，Fuzhou 35oooo，China

【Abstract】 Objective Study the diagnostic value of peripheral blood leukocyte classification and related inflammatoryindicators in distinguishingacute upperrespiratory infections fromotherfebrile diseases，andcombine multiple indicators to constructa predictivemodel.MethodsAretrospective analysis was conductedon theblood routine results of 165 patients with'fever within three days'as the main complaint who visited Shaxian District General Hospital in Sanming City from January 2O23 to December 2O24.According to the causes of fever，fever patients were divided into acute upper respiratory infection group of 1OO cases and other fever disease group of 65 cases.And 1OO healthy individuals during the same period were selectedas the control group.Compare the differences in peripheral blood leukocyteclasificationand related inflammatory indicatorsbetweenthe fever disease group and the control group，acute upper respiratory infection group and other fever disease groups， including neutrophil percentage （NE % ）， lymphocyte percentage （LY % ），monocyte percentage （ MO% ）， neutrophil to lymphocyteratio （NLR），monocyte to lymphocyteratio （MLR），systemic inflammatoryresponse index （SIRI），and systemic immune inflammatory index （SI）.Logisticbinaryregressionanalysis of risk factors foracuteupper respiratory infectionsandconstruction of a nomogram model.ROC analysis evaluation of various risk factors and the nomogram model for screening the diagnostic efficacy of acute upper respiratory infections.ResultsThe levels of LY % ，MO % ，and MLR in the acute upper respiratory infection group were significantly higher than those in other feverdisease groups（ P =0.002，

【Key words】 Respiratory tract infections；Leukocytes； Inflammatory cell; Systemic inflammatory responseindex;Systemic immune inflammationindexDOI：10.19522/j.cnki.1671-5098.2025.05.005

急性上呼吸道感染是一种炎症性疾病，可有急性发热、咳嗽、鼻塞流涕等典型的临床表现1。（剩余7464字）