磁共振成像单光子发射计算机断层成像术/低剂量CT融合显像检查在诊断肺癌骨转移中的效能对比研究

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Acomparative study of the efficacy of magnetic resonance imaging and photon emission comput

tomography low-dose CT fusion imaging in the diagnosis of bone metastases in lung cancer

LiuMengwen，Zhao Sen

DepartmentofImaging，theFirstAffliatedHospitalofHenanUniversity，Kaifeng475o2，Cina

Corresponding author： Zhao Sen， Email： 408265788@qq.com

【Abstract】 Objective To evaluate the diagnostic eficacy of magnetic resonance imaging （MRI）， single photon emisson computed tomography （SPECT）and low-dose CT fusion imaging in bone metastases of lung cancer.

MethodsA totalof1O8 patients with suspected bone metastases of lung cancer who were treated inthe First Affiliated Hospitalof Henan University from February 2O22 to February 2024 were selected.MRIand SPECT/CT were performed on all patients to compare the diagnostic efficacyof bone metastases of lung cancer，andthe sites of bone metastases and types of bone destruction of differentpathological types oflung cancer were analyzed.Results Pathological resultsshowed that 86 of 1O8 suspected lung cancer patients with bone metastasis were positive， accounting for 79.6% ，and 22 were negative，accounting for 20.4% . The sensitivity，specificity and accuracy of SPECT/ low-dose CT for bone metastasis of lung cancer （91.86 % ， 90.91% ， 91.67% ）werehigher than thoseofMRI 0 86.05% ， 81.82% ， 85.19% ），butthedifferencewasnot statisticallysignificant（ P>0.05 ）. The proportion of bone destruction，cortical bonedestruction，and changes inbone marrow density inpatients withbone metastasis is higher than that in patients without metastasis，and the difference is statistically significant（ P <0.05）.There was no significant differencebetween the bone metastasis sitesand bone metastasis types in diferentpathological typesof lung cancer patients （P>0.O5）.ConclusionBoth SPECT/low-dose CT fusion imaging and MRI can detect bone metastases of lung cancer，but SPECT/low-dose CTfusion imaging has better diagnostic sensitivity，specificity and accuracy.

【Key words】 Multiparametric magnetic resonance imaging; tomography； Emision -computed single -photon; Tomography，spiral computed; Lung cancer; Bone metastasis

肺癌是我国常见的恶性肿瘤，其发病率逐年上升，该疾病发展较快，早期症状隐匿，不易检出，在临床被诊出时多为中晚期[1。（剩余6653字）