苯磺酸瑞马唑仑和右美托咪定在脑血管造影中的应用比较

打开文本图片集

【Abstract】 Objective To compare the sedative effects remazolam benzoate or dexmedetomidine in cerebrovascular angiography（DSA）and to providean effctive and safe method for clinical treatment.MethodsA total 76 patients with DSAadmited toour hospitalfrom March 2022 to December2O23 were randomly divided into two groups： Remazolam benzoate （R） group and dexmedetomidine （D） group. Group R was given 0.15mg/kg remazolam intravenously，pumped within 3min，and then 0.2mg⋅kg-1⋅h-1 remazolam for maintenance during the operation. Group D was given 0.5μg⋅kg-1⋅h-1 dexmedetomidine intravenously，pumped within 15 min，and then given 0.5μg⋅kg-1⋅h-1 dexmedetomidine for maintenance during the operation.Heart rate（HR），mean artery pressure（MAP），respiratory rate（RR），SpO2，sedation-agitation score andadverse reactions were recorded before administration and 5 min after administration.ResultsBoth groups were able to complete the examination successfull.There was no significant diference in preoperative general informationand vital signs between the two groups （ P>0.05 ）. Compared with preoperative results，MAP and SP02 and RR in both groups decreased to a certain extent，but the difference was not statisticallsignificant.The MAP group Dwas significantly decreased，and he difference was statistically significant （ P <0.05）. Riker sedation - agitation score decreased in both groups，the difference was statistically significant （ P <0.05），but Riker sedation- agitation score was lower in group R，the difference was statistically significant （ P <0.05）.In R group，sedation was faster，the diference was statistically significant （ P <0.05），and the time to wakeup and leave the resuscitation room was shorter（ P <0.05），and the recovery process from anesthesia was faster.There was no significant diffrence in operation time （ P>0.05 ）. Among the adverse reactions，there were more intraoperative body movement in group Dand more hiccup in group R，but the differences were not statistically significant （ P>0.05 ）.ConclusionThe application remazolam besylate in cerebral angiography has good sedative effct and less adverse reactions，which can make the examination safe and smooth.

【Key words】 Remazolam；Dexmedetomidine; Cerebral angiography

脑血管造影（DSA）是诊断脑血管疾病的金标准。（剩余3918字）