肺癌病人癌症相关认知障碍潜在剖面分析及影响因素

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AbstractObjective：Toexplorethelatentprofilsofcognitivefunctioninlungcancerpatientsandtheirifluencingfactors.Methods：A totalof296lungcancerpatientswhovisitedtheoncologydepartmentofatertiarygradeAhospitalinChongqingfromJanuarytoAugust 2025wereselectedasthesurveysubjects.Generalinformationquestionnaire，unctionalAsesmentofCancerTherapy-Cognitive FunctionScale，ExerciseAdherenceScale，andSelf-Rating AnxietyScalewereusedforinvestigation.Latentprofileanalysiswas employedtoexplorethelatentprofilesofcancer-relatedcognitiveimpairment，whileunivariateanalysisandmultiomialLogistic regresioanalysiswereusedtoinvestigatetheinfluencingfactorsoflatentprofilesincancerrelatedcognitiveimpairmentpatients. Results：Cancerrelatedcognitive impairmentpatientscouldbeclasifiedintothreelatentprofiles：highcognitivefunctiongroup （67.2%） ） moderate cognitive function group （22.6%） ，and low cognitive function group （10.1% ）.Multinomial Logistic regression results showed that educatioalleveloggeeseeendietyeiueningfctsftetpolofgiifcug cancer patients（all P<0.05 ）.Conclusions： Cancer-related cognitive function in lung cancer patients exhibits group heterogeneity.It suggeststhathealthcareprofesionalsshoulddevelomoretargetedinterventionmeasuresbasedontheinfluencingfactorsofdiferent categories of lung cancer patients' cognitive function levels.

Keywordslungcancer;cognitivefunction；cancerrelatedcognitiveimpairment;latentprofileanalysis;influencingfactors；ocology nursing

全球癌症统计数据（GLOBOCAN显示，2021年肺癌新发例数达250万例，死亡例数达181.7万例，发病率和死亡率已在恶性肿瘤中位于前列，且其难治性病人往往背负极大的医疗负担[2]。（剩余10122字）