基于“心-脑-肠”轴探讨从心脾同治理论辨治冠心病合并焦虑抑郁
[关键词]冠心病；焦虑抑郁；心-脑-肠轴；心脾同病；心脾同治；健脾补心；逐癡化痰 [中图分类号]R256.2； R749.4+1 （204号 [文献标志码]A [文章编号]0256-7415（2026）06-0199-06 DOl：10.13457/j.cnki.jncm.2026.06.031
Exploration on Syndrome Differentiation and Treatment of Coronary Heart Disease Complicated by Anxiety and Depression from the Perspective of Simultaneous Treatment of Heart and Spleen Based on the "Heart-Brain-Gut" Axis Theory
LI Sijin1，XIE Longyun1，NIE Yichao1，JIA Xiaoqing²
1.AfiliatedGuangdongHospitalofIntegratedTraditionalChineseandWesternMedicineofGuangzhouUniversityofChineseMedicine， FoshanGuangdong5282oo，China；.GuangdongProvincialHospitalofIntegratedTraditioalChineseandWesternMedicine，Foshan Guangdong 528200，China
Abstract：Coronary atherosclerotic heart disease complicated by anxiety and depresion is a highly prevalent clinicalconditionthatseverelyaffectsprognosisandqualityoflifeof patients.Thisarticle，basedonthe"heart-braingut"axis theoryand integrating the traditional Chinese medicine（TCM）theoriesof visceral manifestation，qi，and blood，focusesonthe"deficiencyintheorigin"characterized bydeficiencyof heartand spleenandthe "excesi the superficiality"characterized by the intermingling of phlegm，blood stasis，anddepresion.Deficiency intheoriginand excess in the superficiality interactto form aviciouscycleof "disease leading to depression and depression aggavating disease"through the "heart-brain-gut"axis.Treatment emphasizes the simultaneous treatment ofthe heartand spleen， aiming to invigoratethespleenand nourishtheheartto strengthen theroot，andtodispel stasisandresolvephlegm to treat the branch manifestations.This approach seeks to achieve functional coordination of the "heart-brain-gut" axis by regulating intestinal microbiota，neurotransmiters，and thefreeflowofqiandblood，therebyprovidingatheoretical basis and new insights for the clinical prevention and treatment of the "psycho-cardiological diseases."
Keywords：Coronary heart disease；Anxiety and depression；Heart-brain-gut axis；Disease involving heart and spleen；Simultaneous treatment of heartand spleen； Invigorating spleen and nourishing heart；Dispelling stasis and resolving phlegm
冠心病（CHD）是由于冠状动脉发生粥样硬化病变引起管腔狭窄或闭塞，导致心肌缺血、缺氧或坏死而引发的心脏疾病。（剩余10836字）