基于数据挖掘分析治疗肺结节用药规律

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[关键词］肺结节；数据挖掘；用药规律；化痰散结；名医经验；

[中图分类号］R563 [文献标志码］A [文章编号]0256-7415（2025）06-0025-07

DOl：10.13457/j.cnki.jncm.2025.06.005

Analysis of Medication Rules of GAO Xue for Treating Pulmonary Nodules Based on Data Mining

YETinglin¹，GAO Xue²，LUO Ruiqi¹，LIUYu²

1.TheFourthScholofClinicalMedicine，GuangzouUniversityofChineseMedicine，ShenzhenGuangdong518O33，China；2.Shenzn Traditional Chinese Medicine Hospital，Shenzhen Guangdong 518O33，China

Abstract：Objective：To analyze the medication rules of Professor GAO Xue in treating pulmonary nodules with the application of data mining based on the Traditional Chinese Medicine Inheritance Computing System.Methods： Case data of lung nodule patients who visited ProfessorGAO Xue's clinic from September 2021 to December 2022 were collcted and organized to construct an outpatient database.Traditional Chinese Medicine Inheritance Computing System（V3.O）was used toexplore the frequency，fourqi，fiveflavors，meridianentries，eficacy，association rules， and corecombinations of prescription medicinals，and summarize Professor GAO Xue's medication experience in preventing and treating pulmonary nodules.Results：A total of 121 prescriptionswereincluded，involving 119 Chinese medicinals，with a totalusage frequencyof2047times.There were 3Ocommonlyused Chinese medicinals， mainly ncluding phlegm-resolving medicinals，heat-clearing medicinals，exterior-releasing medicinals，deficiencytonifying medicinals，andqi-regulating medicinals；the statisticsfor thefourqishowed that warm medicinals were the most common，followed bycold medicinals；the most commonlyused medicinalflavors were acrid and biter；the most commonly meridian entries were the lung，the spleen，and the stomach meridians.There were 31 commonly used medicinal combinations，and three commonly used characteristic couplets were obtained through clustering analysis using K-means algorithm combined with clinical experience.Conclusions：Profesor GAO Xue's clinical treatment of pulmonary nodulesis basedonthe theoryof "latent pathogen inthelung"，withthe main focus on dispelling pathogens， resolving phlegm and dissipating masss throughout，and supplemented by methods such as clearing heat and dispeling dampness，promoting blood circulation and removing blood stasis，and diffusing the lung and moving qi.

Keywords：Pulmonary nodules；Data mining；Medication rules；Resolving phlegm and dissipating masses; Experience of renowned doctors；GAO Xue

肺结节是指影像学表现为直径 ⩽3cm 的局灶性、类圆形、密度增高的实性或亚实性肺部阴影，可为孤立性或多发性，不伴肺不张、肺门淋巴结肿大和胸腔积液。（剩余8147字）