急性戊型肝炎伴肝纤维化一例

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中图分类号：R575.1 文献标识码：B 文章编号：1000-503X（2025）04-0666-07

DOI：10.3881/j.issn.1000-503X.16354

Acute Hepatitis E Complicated With Liver Fibrosis： Report of One Case

LIU Xinyue1，RAO Huiying²，HUANG Rui²

1 Department of Nephrology ， 2 Instituteof Hepatology Peking University，Peking University People’s Hospital，Beijing 144，China

Corresponding author：HUANG Rui Tel：O10-66583771，E-mail：strangehead@163.com

ABSTRACT：Hepatitis E is the liver inflammation caused by a hepatitis E virus infection.Immunocompetent patients with acute hepatitis E can spontaneously clearthe infection，whereas immunosuppressed patients may not beableto clear the hepatitis E virus infection and develop chronic hepatitis.Most patients with hepatitis Eareasymptomaticand present only with mild and persistent liver function abnormalities.Thisarticle reportsa case of hepatitisEinanimmunocompetent adultwith elevated aminotransferases asthemain manifestation.Hepatic fibrosis was detected by hepatic puncture biopsy.This report aims to remind other physicians to evaluate liver fibrosis when encountering acute hepatitis E，especially in patients with chronic liver disease.

Key words：hepatitis E；liver fibrosis；abdominal CT；liver histology

ActaAcadMedSin，2025，47（4）：666-672

戊型肝炎病毒（hepatitisEvirus，HEV）作为全球急性病毒性肝炎的主要致病原，其流行病学负担已引发广泛关注。（剩余12638字）