壮药鹰不扑(虎刺總木)的质量标准提升研究

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中图分类号R284;R917 文献标志码A 文章编号 1001-0408(2025)21-2645-06

DOI 10.6039/j.issn.1001-0408.2025.21.05

ABSTRACTOBJECTIVETo improve thequality standard of Zhuang medicine Yingbupu (Aralia armata).METHODS A total of23batchesofYingbupu(A.armata)werestudied.Theirmacroscopiccharacteristicsandpowdermicroscopicfeatureswere observed.TLCwasemployedforthequalitativeidentificationofoleanolicacidandaralosideA.Itemssuchas watercontent,total ash,acid-insolubleash,andethanol-solubleextractweredeterminedacordingtothemethodsspecifiedinthe202Oeditionofthe ChinesePharmacopoeia(partV).UPLCfingerprintwas establishedfor23batchesofsamplesbyusing SimilarityEvaluation SystemforChromatographicFingerprintsofTraditionalChineseMedicine(2O12edition),andthecontentsofoleanolicacidand aralosideAweredetermined.RESULTSThepowdermicroscopiccharacteristicsofthemedicinalmaterialweredistinctive. OleanolicacidandaralosideAweredetectedbyTLCinall23batches.Amongthe23batchesofsamples,thecontentrangesof moisture,total ash,acid-insoluble ash,and ethanol-soluble extract were 6.9% to 10.4% , 1.8% to 6.8% , 0.1% to 1.9% ,and 2.8% (204号 to 8.4% ,respectively.Basedonthe UPLC fingerprint,a total of15common peaks were obtained,and9of these common peaks were identified.The content ranges of oleanolic acid and araloside A in the 23 batches of samples were 0.86% to 2.69% and 0.16% (204号 to 1.10% ,respectively.CONCLUSIONS This study has added items suchas moisture and total ash content fingerprint,TLC identification.Apreliminaryqualitystandardhasbeenestablishedforthemedicial materialofYingbupu(A.armta),stipulating that the moisture content should not exceed 11.0% ,the total ash content should not exceed 5.0% ,theacid-insolubleash content should not exceed 2.5% ,the ethanol-soluble extract content should not be less than 4.0% ,and the contents of oleanolic acid and aralosideA should not be less than 1.00% and 0.45% (calculated bya dried basis),respectively.

KEYWORDSYingbupu;Aralia armata;quality standards; oleanolicacid;aralosideA

鹰不扑是广西壮族地区传统的民间药物,来源于五加科植物虎刺惚木Araliaarmata(Wall.)Seem.或黄毛惚木AraliadecaisneanaHance的干燥根。(剩余10344字)

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