小四五汤治疗痛风性关节炎的疗效及对疼痛的缓解效果

[关键词] 小四五汤;依托考昔;痛风性关节炎;疗效;疼痛

[中图分类号] R589.7          [文献标识码] B          [文章编号] 1673-9701（2021）15-0133-04

The effect of Xiaosiwu Decoction on gouty arthritis and its pain relief effect

GU Jian1   CHEN Wei2

1.Department of Endocrinology， Quzhou Municipal Hospital of Traditional Chinese Medicine， Quzhou   324000， China; 2.Department of Gastroenterology， Quzhou Municipal Hospital of Traditional Chinese Medicine of Zhejiang Province， Quzhou   324000， China

[Abstract] Objective To observe the curative effect of Xiaosiwu Decoction on gouty arthritis and its pain relief effect. Methods The 102 patients with gouty arthritis diagnosed and treated in our hospital from January 2019 to January 2020 were screened out and divided into group A （51 cases） and group B （51 cases） according to different treatment plans. Group A took Etocoxib orally， 120 mg/time， 1 time/d for 1 week. Group B took Xiaosiwu Decoction 1h after meals， 200 mL/time， 1 dose/d for 1 week. The clinical symptoms （ioint swelling score， activity limitation score）， pain intensity （VAS）， C-reactive protein level， and overall efficacy of the two groups after treatment were compared. Results The joint swelling score and activity limitation score （0.65±0.18 points， 0.45±0.12 points） of group B after treatment were lower than those of group A （0.97±0.21 points， 0.70±0.16 points）， P<0.05. The post-treatment VAS score （2.21±0.83 points） of group B was lower than that of group A （4.19±1.04 points）， P<0.05. The level of C-reactive protein （10.25±2.31 mg/L） after treatment in group B was lower than that of group A （17.69±5.14 mg/L）， P<0.05. The total effective rate of group B （92.2%） was higher than that of group A （76.5%）， P<0.05. Conclusion Xiaosiwu Decoction is effective in treating gouty arthritis. It can significantly reduce joint swelling and activity limitation， relieve pain， and reduce C-reactive protein levels. It has high total effective rate and is worthy of clinicians' popularization.

[Key words] Xiaosiwu Decoction; Etocoxib; Gouty arthritis; Curative effect; Pain

痛風性关节炎为临床常见病，男性的发病率高于女性[1]。（剩余4686字）

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