免疫球蛋白联合地塞米松治疗急性吉兰-巴雷综合征的效果

打开文本图片集

[关键词] 吉兰-巴雷综合征;免疫球蛋白;地塞米松;效果

[中图分类号] R512.32          [文献标识码] B          [文章编号] 1673-9701（2021）15-0101-03

The efficacy of immunoglobulin combined with dexamethasone in the treatment of acute Guillain-Barre syndrome

LIN Xia

Department Ⅰ of Neurology，the First People′s Hospital of Tianshui City in Gansu Province，Tianshui   741000，China

[Abstract] Objective To investigate the efficacy of immunoglobulin combined with dexamethasone in the treatment of acute Guillain-Barre syndrome. Methods A total of 45 patients with acute Guillain-Barre syndrome admitted to our hospital from January 2016 to October 2020 were analyzed retrospectively，and they were divided into the immunoglobulin combined with dexamethasone group（n=23） and the single immunoglobulin group （n=22）， respectively. The therapeutic efficacy and clinical outcome of patients in the two groups were compared， respectively. Results The overall response rate in the immunoglobulin combined with dexamethasone group was significantly higher than that in the single immunoglobulin group， while the ineffective rate was significantly lower than that in the immunoglobulin treatment group，with statistically significant differences（P<0.05）. The length of stay in the immunoglobulin combined with dexamethasone group was（15.0±5.5）d， which was significantly shorter than that of（26.0±8.8）d in the single immunoglobulin group，with statistically significant differences（P<0.05）. Conclusion Immunoglobulin combined with dexamethasone is effective in the treatment of acute Guillain-Barre syndrome，and has broad application prospects at the grass-roots level.

[Key words] Guillain-Barre syndrome; Immunoglobulin; Dexamethasone; Efficacy

吉蘭-巴雷综合征（Guillain-Barre syndrome，GBS）是主要累及周围神经的自身免疫疾病。（剩余5996字）

网站仅支持在线阅读（不支持PDF下载），如需保存文章，可以选择【打印】保存。