冠心病患者冠脉狭窄程度的危险因素分析

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[关键词] ApoE;Hcy;血脂水平;冠心病;冠脉狭窄程度

[中图分类号] R541.4          [文献标识码] B          [文章编号] 1673-9701（2021）15-0046-04

The analysis of risk factors of coronary stenosis in patients with coronary heart disease

WU Yu

The Third Department of Cardiology， the Central Hospital of Jiamusi City in Heilongjiang Province， Jiamusi   154002，China

[Abstract] Objective To analyze the risk factors of the degree of coronary stenosis in patients with coronary heart disease （CHD）. Methods A total of 98 patients with CHD treated in our hospital from February 2018 to March 2019 were selected as the experimental group according to admission time and admission population category. 50 healthy individuals who underwent physical examination in our hospital during the same period were selected as the control group. The levels of ApoE， Hcy and low density lipoprotein （LDL） of the two groups were compared， and the levels of ApoE， Hcy and LDL in patients with different degrees of coronary artery lesions were compared. Univariate analysis was carried out on patients with different degrees of coronary artery stenosis. Results （1）The levels of ApoE， Hcy and LDL in the experimental group were significantly higher than those in the control group， with significant difference （P<0.05）. （2）The levels of ApoE， Hcy， and LDL were the highest in the moderate and severe stenosis group，followed by moderate stenosis group，mild stenosis group and non-coronary stenosis group，with statistically significant differences among these groups（P<0.05）. （3）Hypertension， diabetes mellitus， smoking and LDL were the single factor influencing the degree of coronary artery stenosis （P<0.05）. Hypertension （OR=1.021，95%CI：1.041-1.156）， diabetes mellitus （OR=3.206，95%CI：1.465-7.526），smoking （OR=3.625，95%CI： 1.563-8.023） and LDL （OR=6.384，95%CI：6.877-21.470） were the risk factors of the degree of coronary artery stenosis in patients with CHD （P<0.05）. Conclusion ApoE， Hcy， LDL， hypertension， diabetes and smoking were all risk factors for the degree of coronary artery stenosis in patients with CHD.

[Key word] ApoE; Hcy; Blood lipid level; Coronary heart disease; Degree of coronary stenosis

冠心病是以冠狀动脉血管发生动脉粥样硬化病变为特征，诱发血管腔狭窄或堵塞的疾病，易导致心肌缺血、缺氧或坏死，进而出现胸痛、恶心、呕吐等临床症状[1]。（剩余5125字）

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