在肺结核细菌检测中运用荧光定量PCR检测法的临床价值

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【摘要】目的：分析在肺结核细菌检测中运用荧光定量PCR检测法的临床价值。方法：本文总共纳入88例观察对象，均是我院2016年5月—2021年5月收治的疑似尘肺合并肺结核患者，对88例患者开展荧光定量PCR与痰涂片抗酸染色检测。将临床诊断作为参照依据，比较两种方法的检测结果。结果：在检出率、敏感度、特异度、阳性预测值以及阴性预测值上，荧光定量PCR明显高于痰涂片抗酸染色检测（P

【关键词】肺结核；细菌检测；荧光定量PCR检测法；临床价值

Clinical value of fluorescence quantitative PCR detection method in the detection of pulmonary tuberculosis bacteria

WEN Xiaoping

Department of Laboratory， Huizhou Occupational Disease Prevention and Control Hospital， Huizhou， Guangdong 516001， China

【Abstract】Objective： To analyze the clinical value of fluorescent quantitative PCR detection method in the detection of pulmonary tuberculosis bacteria. Methods： A total of 88 observation objects were included in this study， all of whom were patients with suspected pneumoconiosis complicated with pulmonary tuberculosis admitted to our hospital from May 2016 to May 2021. Fluorescence quantitative PCR and sputum smear acid-fast staining were performed on 88 patients. The clinical diagnosis was used as a reference to compare the test results of the two methods. Results： The detection rate， sensitivity， specificity， positive predictive value and negative predictive value of fluorescence quantitative PCR were significantly higher than those of sputum smear acid-fast staining（P

【Key？Words】Pulmonary tuberculosis； Bacterial detection； Fluorescence quantitative PCR detection method； Clinical value

肺结核在临床上比较常见，是一种慢性的传染病，患者在感染结核杆菌后不一定及时出现症状，当患者的抵抗力降低情况下才会引起疾病[1]。（剩余4278字）