纤维蛋白原/白蛋白比值与早发冠心病的相关性研究

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Study on Correlation Between Fibrinogen/Albumin Ratio and Premature Coronary Heart Disease

YANG Anni，LI Lamei，ZHOU Tong，FAN Xinyu，CAI Gaojun

【Abstract】ObjectiveToinvestigatethecorelationbetweenfibrinogen/albuminratio（FAR）andprematurecoronaryheartdisease （PCHD）.MetodsConseutiveenollentpatintsundergoingcoroaryangigaphy（aged55yearsforalesandaged65yearsales） wasconducted.ParticipantserestratfiedintothePCHDgroupandthcontrolgroup.Teclinicaldatapatientsinetoroupsere compared，follodbsesoalseid.RsAoedts， including 956malesith6aigedtoteCHgoupnd32tothecotrolgroupSignifcantlyelevadFARlevelsereosedinte PCHD group compared to the control group ⌊0.07（0.06，0.08） vs 0.06（0.05，0.07）， P<0 . 001]. Multivariate logistic regression analysis demonstrated thatFAR，as both acontinuous variable（OR=2.467，95%CI 1.635～3.722， P <0.001）and acategorical variable（OR=1.667，95%CI （202 1.287～2.160，P<0.001 ），wasaindependentcorrelated factor PCHD.Furthermore，thecorelation PCHD increased progressively increasing FAR values.Compared the low-FAR group，the high-FAR group exhibited a 1.667 -fold increase in the levelsassociated PCHD. SubgroupanalyssyderevaledasiifiantposiiecoelatoetenFRandisinealesOR=1.6779CI17， （20 P=0.004 ）.Conclusion FAR was identified as an independent asociated factor for the risk PCHD occurrence.

【Keywords】 Premature coronary heart disease;Fibrinogen/albumin ratio;Gender;Cross-sectional study

随着社会经济的发展和生活方式的变化，心血管疾病（cardiovasculardisease，CVD）已成为全球范围内的主要公共卫生问题之一[1]。（剩余11523字）