缺血心肌细胞中的线粒体能量动力学：机制、功能与应用前景

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Mitochondrial Energy Dynamics in Ischemic Cardiomyocytes ： Mechanisms，Functions and Application Perspectives

XIE Xiaotong，CHEN Xinyun

（Department of Cardiac Function，Chengdu Integrated TCM&Western Medicine Hospital，Chengdu 610oo0，Sichuan，

China）

【Abstract】iohodriaeastetalhubfoelularergetabolis，glatigAprodutiodoxmeostasisdel deathprocesscaalodlypossdaltidicyi， trigeringoxidativestressandmetabolicdrangements.Iardiomycyesitohondriantlyprovideerbutalsoeertpvoalolesn orchestraingcellasurvivalandeathascadesMitohondrialfisionfusiondmiohagyonstituteindispensableprocstat maintainingmitohodrialfuctiodcelularviabilityhreasdregulateddaicsayexaceateishducedijuyisrtice reviewsthealteratiosinitocondrialeergydamicsuringyocardialiscemiaexaminstheontribtoryoleofoidatiesrst cardiomyocyefutiicoetsdatesthastfmeosvngfiofusiodut proposesthatodulatingitochodialdaicsafeoelisightsndthrapeticrategiesforthdagosisndtreatenofiscic cardiomyopathy.

【Keywords】Myocardial ischemia;Oxidative stress;Mitochondrial function;Mitochondrial dynamics

急性心肌梗死（acutemyocardial infarction，AMI）是全球导致发病率和死亡率升高的主要心血管疾病之一，通常由冠状动脉阻塞引起。（剩余12150字）