亲环蛋白A与动脉粥样硬化的相关性研究进展

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The Correlation Between Cyclophilin A and Atherosclerosis

（Departmentof CardiologyThe SecondAfiliated Hospital of Nanjing Universityof Chinese Medicine，Nanjing210017，

Jiangsu，China）

【Abstract】Atheroslerosisisthepathologicalbasisofvariouscardiovasculardiseases.Thisarticlereviewsterelevantmechanissof cyclophilinAioedineucedvelopntofrosleroticlsis，cluingpomotingiatorysoctig targetcelltincogeoisndpotingldablisidtisstIndeeol intervention and therapeutic target identificationin atherosclerosis.

【Keywords】Atheroslerosis;CyclophilinA;Inflammation;Targetcell;Macopageeferocytosis;Lipidmetabolism;Oxiativestre

亲环蛋白是一种普遍存在且高度保守的蛋白质家族，具有肽基脯氨酰顺反异构酶活性，可催化脯氨酸残基处肽键的顺反异构化。（剩余13078字）