甲基转移酶14介导的m6A甲基化在冠心病中的研究进展

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【DOI]10.16806/j. cnki.issn.1004-3934.2025.07.012

m6A Methylation Mediated by Methyltransferase 14 in Coronary Heart Disease

YE Furong，LIAO Wang，WANG Chenye （DepartmentofCardiology，Hainan Afliated Hospitalof Hainan Medical University，Haikou 57o311，Hainan，China）

【Abstract】m6Amethylationmodificationrepresentsthemostprevalentandabundantinteralpost-transcriptionalRNAmodification obserediukayoticellMetylrasfese14iansetialtylatioodfiationpoteiniodinmethlatiodicatio Theobjectiveoftispperistoinvestigatetemechanismofmethyltransferase14-mediatdm6ARAethylationmodificationincooay heartdiseaseandtoreviewthelatestreseachfindings.Thiswillnotonlyenanceourcomprehensionofthemechanismsassociatedwith coronaryeartsseutlopodeoelpspeindotetialgetsfoeeinsevedteamntas potentially lead to new therapeutic avenues.

【Keywords】 m6Amethylation;Methyltransferase14;Coronary heart disease

表观遗传过程（如非编码RNA、DNA和组蛋白修饰）通过调节真核生物中的转录后基因表达广泛影响各种生物过程。（剩余12905字）