心血管-肾脏-代谢综合征视角下动脉粥样硬化性心血管疾病的现状与管理策略

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Current Status and Management Strategies of Atherosclerotic Cardiovascular Disease from The Perspective of Cardio-Renal-Metabolic Syndrome

YIN Yuzhe，LI Zhe，WU Yongjian

（Coronary HeartDiseaseCenter，Fuwai Hospital，ationalCenterforCardiovascularisease，ChneseAcademyofedical

Science and Peking Union Medical College，Beijing 1Ooo37 ，China）

【Abstract】Cardiovascular-kidney-metabolic（CKM）syndromeisasystemicdiseasecausedbythepathophysiologicalinteractions among obesiy，dabeteschonicidneydiseaseandcardiovasculardisease.Atherosleroticcardiovasculardisease（ASCV），soeofthe mostimportantcadiovaslardiseasesitsprevetiondanagentaeteoretomprovetprogosisofadiovascularisaih theintroductionoftheconceptofCKMsyndrome，moreandmoreatentionhasbeenpaidtoASCVDbycombining themanagementofother systemsoutsidethecardiovascularsystem.ThisreviewtakesASCVDinCKMsyndromeastheentrypointtodeplydiscusstheepidemiological status，pathophsiologicalmechanismandtreamentmaagentstategiesofACVDintecontextofCKsydroe.Itiscomededto carryutcomprehensivemanagementof ACVDthoughultidisciplinarydiagosisandtreatmentandestablishasystematicsrenngforall ages to establish an earlier and more eective management plan for this population.

【Keywords】Cardiovascular-kidney-metabolicsyndrome；Atheroscleroticcardiovasculardisease；Type2diabetesmelitus；Chronic kidney disease

随着人口老龄化、不健康生活方式和饮食习惯的改变，心血管疾病（cardiovasculardisease，CVD）、慢性肾脏病（chronickidneydisease，CKD）和代谢性疾病，如2型糖尿病（type2diabetesmellitus，T2DM）、代谢综合征等的患病率不断上升，成为威胁人类健康的主要疾病。（剩余15371字）