中国老年人心血管代谢性共病与认知功能的关系

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Abstract  Objective：To explore between cardiometabolic multimorbidity and cognitive function in Chinese elderly.Methods：18 009 elderly aged 65 and above with follow⁃up records at 2014 and 2018 in Chinese Longitudinal Healthy Longevity Survey（CLHLS） were included as subjects，their basic information were investigated，and the relationship between the cardiovascular metabolic disease（including hypertension，diabetes，heart disease and cerebrovascular disease） number，combination and cognitive function of elderly were analyzed by generalized linear model.Results：The prevalence of cardiometabolic multimorbidity in the elderly was 19.67%.After controlling for confounding factors such as age and gender，Elderly with cardiometabolic multimorbidity had higher risk of cognitive impairment compared to those without cardiovascular metabolic disease［OR=1.18，95%CI（1.08，1.29）］.and had a higher Mini⁃Mental state Examination score［β=1.52，95%CI（1.21，1.90）］.Elderly with hypertension and diabetes［OR=1.28，95%CI（1.06，1.54）］，and with hypertension，heart disease and cerebrovascular disease［OR=1.33，95%CI（1.04，1.70）］ had higher risk of cognitive impairment compared to those without cardiovascular metabolic disease.Conclusions：Elderly with cardiometabolic multimorbidity，especially those with comorbidity patterns including hypertension，have higher risk of cognitive impairment.

Keywords    cardiometabolic multimorbidity； cognitive function； elderly； nursing

摘要  目的：探讨中国老年人心血管代谢性共病与认知功能的关系。（剩余10933字）