基于3DSlicer、主成分分析构建预测神经内镜治疗非急性硬膜下血肿术后脑组织回弹效果模型

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【中图分类号】 R651 【文献标志码】 A 【文章编号】 1672-7770（2026）01-0050-06

Abstract： ObjectiveTo explore the influencing factors of brain tissue rebound efect after neuroendoscopic treatment of non-acute subdural hematoma（NASH），and construct a prediction model based on 3D Slicer and principal component analysis.MethodsA total of 69 patients with unilateral NASH treated via neuroendoscopy at the Second Affiliated Hospital of Bengbu Medical University from April 2022 to July 2025 were enrolled. 3D Slicer was applied to quantify subdural space volume and bone window parameters. After standardizing bone window coordinates，principal component analysis（PCA） was performed.A predictive model for the 3-day postoperative subdural space rebound rate was established using linear regresson and receiver operating characteristic （ROC） curve analysis. ResultsHistory of cerebral hemorrhage（ β=-0.25 ， P=0.040 ）and a more inferolateral bone window（characterized byPC1， β=-0.34 ， P=0.004 ）were independent predictors of the 3-day rebound rate. Taking 49% rebound rate as the cutoff value，the optimal bone window position was determined when the PC1 value dropped to -0.536 . ConclusionsThe model based on 3D Slicer and PCA identifies core factors influencing the 3-day postoperative rebound rate in neuroendoscopic NASH treatment，defines optimal bone window placement， and provides quantitative evidence for preoperative planning and individualized therapy.

Key words： radiomics；3D Slicer; principal component analysis； non-acute subduralnematoma； neuroendoscopy

非急性硬膜下血肿（non-acutesubduralhematoma，NASH）包括慢性和亚急性硬膜下血肿，通常在数周或数月内缓慢进展，随着血肿体积增大出现相应临床症状和体征[1-2]。（剩余9074字）