免疫检查点抑制剂在晚期结直肠癌治疗中的研究进展

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Research Progress of Immune Checkpoint Inhibitors in the Treatment of Advanced Colorectal Cancer/YIN Jianjian， ZHAO Huarong.//Medical Innovation of China， 2025， 22（10）： 165-169

[Abstract]Colorectal cancer is the most common malignant tumor of the digestive system，the incidence of malignant tumors inthe worldranks thethird，thedeathrate isthesecond， andmostofthediscovery islate，causing agreatthreat tothe life and health ofpatients.The emergenceof immunecheckpoint inhibitorshas brought anew opportunity for systemic treatment of patients withadvanced colorectal cancer， showing a good application prospect， and hasbecome anew therapeuticstrategy.This article aims toreview theresearch status andprogressof immune checkpoint inhibitors in the treatment of advanced colorectal cancer.

[Key words] Immunotherapy Colorectal cancer Immune checkpoint inhibitor：

First-author's address： Department 1， Cancer Center， the First Affiliated Hospital of Xinjiang Iedical University， Urumqi 830ooo， China

doi：10.3969/j.issn.1674-4985.2025.10.039

作为消化系统中常见癌种，结直肠癌（colorectalcancer，CRC）发病率和死亡率近年来均呈上升趋势，根据全球癌症统计数据，其发病率在全球范围内位居恶性肿瘤第三位，死亡率高居第二位。（剩余12840字）