逍遥散合酸枣仁汤治疗更年期失眠症的临床效果

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Clinical Effect of Xiaoyao Powder Combined with Suanzaoren Decoction in the Treatment of Menopausal Insomnia/. //Medical Innovation of China， 2025， 22（10）： 102-105

[Abstract]Objective： To explore the application value of Xiaoyao Powder combined with Suanzaoren Decoction in patients with menopausalinsomnia.Method：A total of 96 patients with menopausal insomnia admitted to from December 2021 to February 2024 were selected and divided into two groups according to random numbertable method， with 48cases ineach group.Thecontrol group was given routine treatment， and the observation group was additionaly administered Xiaoyao Powder combined with Suanzaoren Decoction.Theclinicalefficacy，sleepqualityanxietyanddepression，qualityof lifeandtheoccurrenceofadverse reactions were compared between the two groups. Result： The total effective rate of the observation group was 95.86% ， which was higher than 81.25% of the control group （ P <0.05）. The sleep time [ （0.44±0.12 ）scores]，fall asleep time[ 0.50±0.13 scores]， sleep quality [（0.84±0.25 ）scores]， daytime dysfunction [ 0.73±0.20） scores]， sleep disorders [0 0.82±0.17 ）scores]， hypnotic drugs （0.64±0.13） scores] and sleep efficiency [（0.75±0.15） scores] of Pittsburgh sleep quality index （PSQI）， self-rating anxiety scale （SAS） （40.26±5.85 ）scores]， self-rating depression scale （SDS）I （42.56±6.84 ）scores]， with vasomotor symptoms [（5.31±1.13） scores]， physiological symptoms[ （13.40±2.92） scores] psychological symptoms （8.03±1.52） scores] and sexual life [ （4.85±0.72） scores] of menopausal quality of life （MENQOL） were lower than those of the control group [ （0.62±0.16） ， （0.78±0.17 ， （ 1.15±0.17 ， 1.11±0.22 ， 1.13±0.15 ， 0.82±0.14） ， （1.02±0.23） ， 48.07±6.24） ， （48.95±5.60 ， （6.91±1.42 ， （17.83±3.14） 元 （10.91±2.06） and （6.33±1.14） scores]， the differences were statistically significant （ P <0.05）. No adverse reactions occurred inboth groups during treatment.Conclusion： Xiaoyao Powder combined with Suanzaoren Decoction can improve the therapeutic efect of patients with menopausal insomnia， reduce insomnia， anxiety and depression， improve the quality of life， and high safety.

[Key words] Menopause Insomnia Xiaoyao Powder combined with Suanzaoren Decoction Sleep quality

Anxiety Depression

First-author's address： Department of Traditional Chinese Medicine， Rescu ， 336000， China

doi：10.3969/j.issn.1674-4985.2025.10.024

更年期是女性必经生理过程，普遍发生在绝经阶段，与卵巢功能衰退、激素水平异常等有关-2]。（剩余5051字）