超声引导下射频消融术治疗混合性甲状腺结节对患者术后应激及体积缩小率的影响

Effect of Ultrasound-guided Radiofrequency Ablation on Postoperative Stress and Volume Reduction Rate of Patients with Mixed Thyroid Nodules/MIN Yonghua， ZHU Yu， JIANG Hui. //Medical Innovation of China， 2025， 22（10）： 050-053

[Abstract]Objective： To explore the efect of ultrasound-guided radiofrequency ablation on postoperative stressandvolumereductionrateofpatients withmixed thyroidnodules.Method：Atotalof 100patients with mixed thyroid nodules admitted to theFifth Hospital of Nanchang from January 2022 to April 2023 were retrospectively selected and divided into ethanol ablation group （n=47） and radiofrequency ablation group （n=53） according to different microtraumatic treatment methods.The ethanol ablation group underwent ultrasound-guided anhydrous ethanol ablation， and the radiofrequency ablation group underwent ultrasound-guided radiofrequency ablation. The stress condition， nodules volume reduction rate and clinical efficacy of the two groups were compared. Result：Compared with ethanol ablation group， the levels of Creactive protein （CRP），interleukin-6 （IL-6）and

tumor necrosis factor- α （TNF- α ）1 d after surgery in radiofrequency ablation group were lower （P<0.05） ·Compared with ethanolablation group， the nodulesvolume reduction rate in radiofrequency ablation groupl month， 3， 6， 9， 12 months after surgery were higher （ （P<0.05） . The total efective rate of radiofrequency ablation group was 92.45% ， which was higher than 72.34% of ethanol ablation group （P<0.05） . Conclusion： Ultrasound-guided radiofrequency ablation in the treatment of mixed thyroid nodules can efectively reduce the stressresponseof patients and reduce the nodules volume.

[Key words] Radiofrequency ablation Mixed thyroid nodules Postoperative stress Volume reduction rate

First-author's address： Department of Ultrasound Room， the Fifth Hospital of Nanchang， Nanchang 330000， China

doi：10.3969/j.issn.1674-4985.2025.10.012

甲状腺结节是甲状腺内的异常增生组织，可在甲状腺组织内形成一个或多个小的团块，混合性甲状腺结节指的是结节内部同时包含囊性、实性组织结构，部分患者伴有钙化或出血性改变-2]。（剩余5816字）