凌霄痛风颗粒提取工艺及质量控制研究

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1.贵州中医药大学药学院，贵州贵阳550025；2.贵州中医药大学第二附属医院药学部，贵州贵阳550003

【中图分类号】R284.2 【文献标志码】A 【文章编号】1007－8517（2025）09-0059-06

DOI： 10.3969/j .issn.1007-8517.2025.09. zgmzmjyyzz202509014

Research on the Extraction Technology and Quality Control of Lingxiao Tongfeng Granules

ZHANGQiang1 YANG Renhui²YANG Yuanfeng² LOU Yuling² ZHOU Xunrong 1，2 W

1.Scholof Pharmacy，Guizhou Universityof Traditional Chinese Medicine，Guiyang 55o025，China；2.Departmentof Pharmacy，theSecondAfiliated Hospital ofGuizhou UniversityofTraditional Chinese Medicine，Guiyang 550o03，China

Abstract：ObjectiveOptimizethe extraction process，and establish thequalitystandardof Lingxiao Tongfeng granules.MethodsWiththecontentofhesperidinandthepasteyieldrateastheevaluationindexes，thebstextractionprocessofLingxiaoTongfeng granules wasselectedbytheorthogonal test method；According totheprovisionsof ChinesePharmacopoeia granules，thecaracter， hesperidincontentandthinlayeridentification（TC）wereestablished.ResultThebestextractionprocessforLingxiaoTongfeng granuleswasadd8timesofwaterfor3Ominuteseachtime；thethinlayeridentificationmethodofCampsisgrandiflora，PlantagodepressaWilldandCitrusreticulataBlancowas established，andthecontentof hesperidininLingxiaoTongfengwasdeterminedConclusionTheextractioprocssestablishdintisstudyisstablendreliable，andthequalitativeandquantitatiemethodetablishdis convenient and reliable，which can be used as the quality control method of Lingxiao Tongfeng granules.

KeyWords：Lingxiao Tongfeng Particles；Orthogonal Test；Quality Control；TLC；Hesperidin

凌霄痛风颗粒原方是贵州中医药大学第二附属医院风湿免疫科治疗痛风的临床验方。（剩余7615字）