ki67、p16在宫颈病变组织中的表达及其临床意义

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【摘要】目的：研究宫颈病变组织中ki67，p16的表达以及临床意义。方法：研究时间自2019年8月至2021年8月随机抽选40例宫颈病变患者的宫颈病变组织作为研究对象，获取组织标本均实施免疫组织化学染色检测，获取ki67，p16蛋白表达情况，分析其临床意义。结果：三组ki67、p16蛋白阳性表达率相比，宫颈癌组显著高于其他两组，宫颈上皮内瘤变组高于宫颈炎组，差异有统计学意义（P

【关键词】宫颈病变组织；ki67；p16；病理技术

Expression of ki67 and p16 in Cervical Lesions and Its Clinical Significance

FEI Bingyou

Huai’an Maternal and Child Health Care Hospital， Huai’an， Jiangsu 223002， China

【Abstract】Objective：To study the expression and clinical significance of ki67，p16 in cervical lesions.Methods：Cervical lesion tissues were randomly selected from 40 patients with cervical lesions from August 2019 to August 2021. All tissue samples were detected by immunohistochemical staining， obtained ki67，p16 protein expression and analyzed their clinical significance.Results：The positive expression rates of ki 67， p16 protein in cervical cancer group were significantly higher than those in the other two groups，and the positive expression rates of ki67， p16 protein in cervical intraepithelial neoplasia group was higher than that in cervicitis group（P

【Key words】Cervical lesion tissue； Ki67；P16； Pathological technology

宫颈癌的形成通常具备一个较长的过程，因此早期防治工作具有重要的意义，通过筛查宫颈癌病变的风险性，给予针对性的干预措施，有助于降低癌变风险，在保障女性健康方面意义重大[1-2]。（剩余3068字）