基于3D-SIicer软件多模态影像融合在经鼻蝶垂体瘤微创手术的应用研究

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【中图分类号】 R739.41;R651 【文献标志码】 B 【文章编号】 1672-7770（2025）04-0456-05

Application of multimodal image fusion based on 3D-Slicer software in transsphenoidal surgery planning for pituitary tumors PAN Didi，GAO Zhibo， XIE Lanjun，GUO Jingpeng，WANG Yongzhi，LI Qi，GUO Hongjun. 236OOo，China

Corresponding author ： GUo Hongjun

Abstract：ObjectiveTo explore theapplication of multimodal image fusion basedon 3D-Slicer software in assisting transsphenoidalsurgeryplanningforpituitary tumors．MethodsTheclinical data of46patients who underwenttransshenoidal microsurgery forpituitary tumorsinFuyang Hospital fromJanuary 2023to August 2024 were retrospectively analyzed.According to the treatment plans，theywere divided intothe experimental group（24 cases）and thecontrol group（22 cases）.The experimental group underwent treatment withthe assistance of 3D-Slicer software for minimallinvasive surgery，while the control group received traditional transnasal microsurgery （without3D-Slicer assistance）.The postoperativecomplications，operation duration，postoperativehospital stay，and blood loss were compared between the two groups.ResultsThere were no significant differences between the patients intheexperimental groupandthecontrol group in termsof age，gender，visualfield defect，tumordiameter， and surgical method（ P>0.05 ）.Compared with the control group，the experimental group had shorter operating time and less intraoperative blood loss，which was statistically significant（ P<0 . 05）．There was no statistically significance in postoperative hospital stay time between the two groups（ P>0.05 ）. Compared with the control group， the total complicationrate intheexperimental groupwas lower，and thediffrence was statistically significant（ P< 0.05）.ConclusionsThe preoperative application of 3D-Slicer software can provide surgeons with more abundant visualizedanatomical information，intuitivelyreflecting thecomplex structuresofthesphenoid sinusand tumor location.Thethree-dimensional visualizedanatomical structure ofthelesioncan help doctorsformulatemore comprehensive preoperative plans，improve the success rate of surgery，and reduce surgical complications，which is worthy of promotion in clinical practice.

Key words：3D printing；multimodal fusion；three-dimensional reconstruction；pituitary tumor;transsphenoidal surgery

垂体瘤是神经外科常见的颅底病变之一，可发生于任何年龄，约占颅内肿瘤的 10%～15% ，主要由细胞基因异常、激素水平紊乱、家族遗传导致，患者主要表现为瘤体压迫造成的相关症状和激素分泌异常症状[1-3]。（剩余7690字）