额部脑膜瘤与胶质母细胞瘤碰撞瘤1例并文献复习

病例报告·

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【中图分类号】 R739.41 【文献标志码】 B 【文章编号】1672-7770（2025）02-0237-04

Abstract：ObjectiveTo investigate the clinical manifestations，diagnosis，pathogenesis，and treatment of primary intracranialcolision tumors.MethodsThe clinical dataofone patientwith primary intracranialcolision tumor treated inthe Departmentof Neurosurgery，Lianyungang First People's Hospital were analyzed retrospectively. The relevant literaturewerereviewed.Thesurgerywasperformed viaamodifiedpterional approach toresect the intracranial mass，andpostoperativeadjuvantradiochemotherapy wasadministered according tothe STUPP protocol. ResultsThe patient presented with dizziness，headache withnausea andvomiting for3days.MRI showed the presence of meningiomaand glioblastoma（GBM）in adjacent regions of the left cerebral hemisphere.Postoperative pathology confirmed meningioma（WHO GradeI）and GBM（WHO Grade IV）．MRI examination at the8-month follow-up showed that the tumorrecurredattheoriginal site.ConclusionsIntracranial collsion tumorsare often composed of meningioma and GBM. Clinical manifestations and imaging findings lack specificity，and the etiology is complex，involvinggenetic，environmental，andimmunological factors.Furtherresearch isneededtoclarifytheir natural course and exact mechanisms and to explore more effective treatment strategies.

Key words：meningioma；glioma；collision tumor；GBM

颅内碰撞肿瘤代表在同一脑区出现两种组织学上不同的原发肿瘤，这种情况临床罕见[1]。（剩余8616字）