外周血清Sema3E蛋白水平与急性心肌梗死患者近期死亡的相关性分析

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[关键词]急性心肌梗死；经皮冠状动脉介入；信号素3E;死亡

[中图分类号] R542.22［文献标志码]A [文章编号] 2097-5716（2025)05-0672-09

DOI: 10.13308/j.issn.2097-5716.2025.05.009

［引用格式］,.外周血清 Sema3E蛋白水平与急性心肌梗死患者近期死亡的相关性分析[J].实用心电与临床诊疗，2025，34(5)：672-680.

Correlation analysis between peripheral serum Sema3E protein levels and recent death of patients with acute myocardial infarctionYIN Yuchun， CHEN Tianping（Department of Cardiovascular Medicine,the First Affiliated Hospital of Bengbu Medical University，Bengbu Anhui 233OOO,China)

[Abstract]ObjectiveTo investigate the correlation between peripheral serum Semaphorin 3E（Sema3E） protein levels and recent death of acute myocardial infarction （AMI） patients undergoing emergency percutaneous coronary intervention（PCI).MethodsA totalof147patients treated by PCI were selected，including 67 AMI patients and 8O patients with stable coronary artery disease.All participants were followed up for an average of 6 months （ranging from 3 to12 months），with al-cause death as the endpoint event.Basedon the follow-up outcomes，patients were categorized into a survival group（139 cases）and a death group（8cases） to analyze the correlation between peripheral serum Sema3E protein levels and their recent death.A subgroup analysis of the 67 AMI patients was performed.These patients were further divided into an AMI survival group(（61 cases）and an AMI death group(6 cases）based on the follw-up results.The relationship between Sema3E protein levels and recent death of AMI patients after emergency PCI was explored.ResultsThere were statistically significant differences in age，neutrophil count（NE），hemoglobin，NT-proBNP，and Sema3E protein level between the survival and death groups （all P

[Key words] acute myocardial infarction； percutaneous coronary intervention； Semaphorin 3E；death

从2000年以来，急性心肌梗死（acutemyocardialinfarction,AMI)的死亡率整体呈上升趋势[1]。（剩余16717字）