基于数据挖掘探究中医药治疗喉源性咳嗽用药规律

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[中图分类号］R256.11 [文献标志码］A [文章编号]0256-7415（2025）13-0017-06

DOl:10.13457/j.cnki.jncm.2025.13.004

Exploring the Medication Patterns of Chinese Medicine in Treating Cough of Laryngeal Origin Based on Data Mining

CHEN Wuxia，HUANG Zhenyan

Zhongshan Hospitalof TradtionalChinese MedicineAfliatedtoGuangzhouUniversityofChinese Medicine，ZhongshanGuangdong ，China

Abstract:Objective:To explorethe prescription and medication patterns of Chinese medicine in treating cough of laryngealorigin using data mining techniques.Methods:Relevantliterature on Chinese medicinetreatment of cough of laryngeal origin was retrieved from the China National Knowledge Infrastructure（CNKI），China Science Periodical Database(CSPD），and Chinese Citation Database（CCD).A database of Chinese medicine prescriptions for cough of laryngeal origin was established using Excel 2O19.The properties，flavors，meridian tropism，and usage frequencyof Chinesemedicinals were statisticallyanalyzed.Asociation patern analysis，hierarchical clustering analysis，and complex network analysis were performed using SPSS Statistics 24.0 and SPSS Modeler 18.O software.Results：A total of 228 prescriptions were included，comprising192 medicinals in19 majorcategories with atotal usage frequency of 2596times.The predominant properties of the medicinals were cold，warm，and neutral；the main flavors were sweet，biter，and pungent；and the primary meridians targeted were thelung，stomach，liver，and spleen.The most commonlyused categories of medicinals werecough-relieving and asthma-controling medicinals，exterior-releasing medicinals，heat-clearing medicinals，phlegm-resolving medicinals，deficiency-tonifying medicinals，and livercalming and wind-extinguishing medicinals.The medicinalswith the top five usage frequency were Cicadae Periostracum，Platycodonis Radix，Armeniacae Semen Amarum，Glycyrhizae Radix et Rhizoma，and Bombyx Batryticatus.Associationruleanalysis identifiedfoursetsof highlycorrelatedmedicinalcombinations.Clusteranalysis divided the medicinals into six clusters.Complex network analysis showed that the main therapeuticcategories of medicinals were wind-dispeling，cough-relieving and asthma-controlling medicinals，heat-clearing and detoxifying medicinals for sore throat，yin-nourishing and lung-moistening medicinals，and qi-regulating and phlegm-resolving medicinals.Conclusion：Cough of laryngeal origin isoftencharacterizedbydeficiencyinterweaved with exess syndrome，with theprimary diseaselocation in thelungand close associations with the liver and spleen.Themain pathogenic factors are wind，heat，dryness，and deficiency.The underlying prescriptions for treating cough of laryngeal origin often include variations of the Zhisou powder，Sangxing Decoction，and Erchen Decoction.The main therapeutic principles are wind-dispelling，cough-relieving and asthma-controling，heat-clearing and detoxifying for sore throat， yin-nourishing and dryness-moistening， and spleen-strengthening and dampness-drying.

Keywords: Cough of laryngeal origin；Medication patterns；Data mining； Chinese medicine

喉源性咳嗽最先由国医大师干祖望教授在《中医喉科学》中提出，认为其主要由咽喉疾病引起，主要症状为阵发性咽痒，可伴随连续性干咳甚至是痉挛性咳嗽，咽痒即咳，痒停咳止；遇到冷空气、刺激性气味等可加重，可伴有咽部异物感，病程长短不一，常反复发作，临床上较为常见。（剩余6397字）