冠状动脉CT血管成像下腔内密度校正差在诊断冠心病患者介入治疗后支架内再狭窄中的应用价值

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Applicationvalue of difinition of corrected coronary opacificationunder artery computed tomography coronaryangiography inthediagnosis of in-stent restenosis after interventional therapy inpatients with coronaryarterydisease

Zou Tingting DepartmentofdiologyunyiHospital，eijingditionalineseedicineHospital，eijingoin

【Abstract】 Objective To explore the application value of difinition of corrected coronary opacification （DCCO）under coronary arterycomputed tomography angiography （CCTA） in thediagnosis of in-stent restenosis （ISR）after interventional therapy in patients with coronary artery disease （CAD）.MethodsThe medical records of 325 patients withCADwhoreceived interventional therapy inthe Shunyi Hospital，Beijing Traditional Chinese Medicine Hospital from June 2021 to December 2024 were retrospectively analyzed.Intracoronary angiography （ICA）was used as the evaluation standard to determine whether there was ISR in each vesel，and the consistency between theempirical diagnosis result of CCTA and the diagnosis of ISR by ICA was evaluated.DCCO was compared betweenthe two kinds of patients.The diagnostic value of CCTA empirical diagnostic result，DCCO and the combinations of the twoon ISR was explored by ROC curve.ResultsConsistency test revealed that the Kappa valueof consistencyanalysisbetween CCTA diagnostic result and ICA for ISR diagnosis was O.675.The DCCO in ICA negative patients was significantly lower than that in positive patients （0.37±O.O6 us. 0.44±0.09， t=. -6.441， P< 0.001）.The areas under the curves （AUC）of CCTA and DCCO in evaluating ISR were 0.817 and O.756 respectively. The AUC of combined detection was 0.897.ConclusionCCTA under DCCO coronary angiography has high clinicalapplicationvalueinthediagnosisofISR in CADpatientsafter interventionaltherapy.Thecombinationof CCTA empirical diagnosis and DCCO can significantly enhance the diagnostic accuracy of ISR and provide strong support for clinical decision-making.

【Key words】 Coronary disease; Coronary restenosis; Multidetector computed tomography; Percutaneouscoronaryintervention

冠心病（coronary artery disease，CAD）是心血管常见病，其核心是冠状动脉粥样硬化，引起血管狭窄至闭塞，最终导致心肌缺血和心肌梗死。（剩余5097字）