小视野高清DWI在鉴别胰腺良恶性肿瘤中的应用

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[中图分类号]R445.2；R735.9 [文献标识码]A DOI：10.3969/j.issn.1672-0512.2026.01.015

Applicationoffield-of-viewoptimizedandconstrainedundistortedsingle-shotDWIindiffrentiationofbenignand malignant pancreatic tumors

CHENChang，MEI Junqing，LU Ying，ZHOU Dan Departmentof Radiology，BenQ Hospital Affiliated of Nanjing Medical University，Nanjing 21oo19，China.

[Abstract]Objective：Toexploretheaplicationvalueoffield-of-viewoptimizedandconstrainedundistortedsingle-shot DWI（FOCUS-DWI）indiferentiting benignandmalignantpancreatic tumors.Methods：Atotalof 55pancreatictumor patientswhounderwentMRIexaminationwereprospectivelycollcted，including23caseswithbenigntumorsand32cases withmalignanttumors.AllpatientsunderwentconventionalDWIandFOCUS-DWI scaning，andtheSNR，CNRandADC valuesof theimageswere measuredand analyzed，andtheimagequalitywassubjectively evaluated.Thepaired t test was usedtoanalyzethediferencesinSNR，CNR，ADCvaluesandsubjectivescoresbetweenconventional DWIimagesand FOCUS-DWI images，while the independent-sample t test was used to anlayze the differences in SNR，CNR and ADC values betweenbenignandmalignanttumors.Results：TheFOCUS-DWIimageshadthehigherscoresofdeformationdistortionand artifacts，anatomicaldetailsandlesionconspicuity，andhigher SNR，CNRvaluescomparedwiththeconventionalDWiages， and all differences were statistically significant （all P<0.05 ）.The ADC values in the conventional DWI and FOCUS-DWI images of benign tumors were higher than those of malignant tumors （both P<0.05 ）.The ADC value of benign tumors in conventionalDWIimageswaslowerthanthatin FOCUS-DWIimages，whiletheADCvalueof malignanttumorsin conventional DWI images was higher than that in FOCUS-DWI images（both P <0.05）.The dispersion of ADC values of benign tumors in the conventional DWI and FOCUS-DWI images were 23.2% （0.64/2.76）and 21.6% （0.65/3.01），while those of malignant tumors were 9.7% （ 0.15/1.55 ）and 10.2% （0.14/1.37），respectively. Conclusion： FOCUS-DWI can improve the image quality of pancreatic tumors and demonstrates promising clinical potential.

[Keywords] Pancreatic neoplasms;Difusion weighted imaging;Magnetic resonance imaging

近年来，胰腺肿瘤的检出率虽逐年升高[1]，但由于胰腺解剖位置较深、周围组织及血管较多，导致病理检查取材困难，且胰腺疾病发病隐匿、早期临床症状不典型，因此胰腺肿瘤良恶性的早期鉴别存在困难[2]。（剩余7224字）