二维斑点追踪超声心动图评价肥胖患者减重手术后左心房功能变化的研究

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Evaluation of Changes in Left Atrial Function in Obese Patients After Bariatric Surgery Using Two-Dimensional Speckle Tracking Echocardiography

ZHU Tingting1，2，ZHAO Jingjing 1，2 ，ZHANG Jiayu²，XUE Jiping² （1. School of Medical Imaging，Shanxi Medical University，Taiyuan O30o01，Shanxi， China;2.Departmentof Ultrasound，Third HospitalofShanxi MedicalUniversity/Shanxi Bethune Hospital，iyuanO3O32，hanxi，hina）

【Abstract】ObjectiveToinvestigatechangesinleftatrialfunctionbeforeandafterbariatricsurgeryinobesepatientsthrough retrospectiveaalysis，provdingrefereceforclinicalreamentandfolowup.MethodsFortyinebesepatitsounderetbaatric surgeryatShanxiBethuneHospitalbetweenDecember2O21andJune2023wereretrospectivelyenroledasthebesegroup.Fiftyhalthy individualsmatchedforageandgender，withnormalbodymassindex（BMI）andbloodpressre，wereselectedasthecontrolgroup. Conventinalechocardiographicparameters weremeasuredinboththecontrolgroupandtheobesegroupatbaselineand6monthsafter bariatricsurgerycudigttioofitralalvelastolicpakfowelocitytoveageofalyastoliceloiitaeal andseptalmitralannulus（averageE/e’）andleftatrialvolumeindex（LAVI）.Two-dimensionalspeckletrackingchocardiography （2D-STE）wasusedtomeasureltralservoirran（LASr），leftatrialonduitstrain（LScd）ndlftatrialoractiletain （LASct）.Clnicalparameters，nvetioalocardiogaphcparameters，ndleftatrialainameterserepardongte groupatbaseli（resurgery），ontsostoerativelyndeotrolop.eoelaneenBdagsinlftal strainparameterswasalsoanalyzed.ResultsAtbaseline，LASrandteabsolutevaluesofLAScdintheobesegroupwereloweraninthe controlgroup，hilethebsolutevaluesofLSctwashgher.6monthsafterbariatrcsurgeryLASndtheabsolutevaluesofLAcdwere significantlyhigherthanatbaselineutstillowerthaninthecontrolgroup，hileteabsolutevaluesofLASctaslowerthanatbaseline. △BMI was positively correlated with △LASr（ r=0 . 496， P<0. 001 ）and positively correlated with △LAScd（ r=0.377，P=0.008） ， but showed no significant correlationwith△LASct（ r=-0.095，P=0.514）. Themultiple linear regression analysisrevealed that△BMI was anindependent influencing factor for both △LASr and △LAScd（ B -value =0 .682， B -value =0 .270，respectively；both P<0， 05 ）

ConclusionLeftalfuctionisipaidisepatitsriatricurgryiprovlefttralfuctindtegefouical BMI reduction is significantly correlated with the degree of improvement in left atrial function.

【Keywords】 Obesity;Left atrial function; Bariatric surgery;Two-dimensional speckle tracking echocardiography

肥胖是心血管疾病的重要危险因素之一[1]，患病率逐年上升，依据《中国成人超重和肥胖症预防与控制指南（节录）》[2]，中国成人超重和肥胖分别为体重指数（body massindex，BMI） ⩾24kg/m2 和 BMI⩾ 28kg/m2 ，按此标准，2018年中国成人的超重及肥胖比例为 51.2% ，预计 2030 年将达到 70.5%[3] 。（剩余10585字）