程序性细胞死亡在心肌缺血再灌注损伤中的研究进展

Programmed Cell Death in Myocardial Ischemia-Reperfusion Injury

YIN Renlin 1，2 ，JIANG Tingbo² （1.DepartmentofCardiologyuzhou NinthHospitalAfiliatedtoSoohow Unversity，uhou15o，Jiangsu，Cina; 2.DepartmentofCardiology，TheFist Afliated Hospital of Soochow University，Suzhou 2150，Jiangsu，China）

【Abstract】Theincidenceofacutemyocardialinfarctionhasnotyetreachedaninflectionpoint.Althoughtimelyrevascularization achievessignifcantficacyinpatintsithacutemyocardialifarctioepefusionterapisaouble-dgedsordpatintsiviably developyocadialijuyfterepefusioownasyocardialishei-epefusionijury.isesfroacompleieplaf pathologicalets，idtisdutiiep thecentralroleofprogrammedcelldeath（PCD）inMRIhasbecomeincreasinglyevident.PCDencompasssapoptosis，utophagy， feroptosis，cuproptosis，optosisdsulfptosisoeoplexinteplaectlyectsardiacfuctioalcoeydit prognosis.TrefoCeprsntsportatiteetiotaretfotamntofdilscusfuigch This article systematically reviews the research progress of PCD in MIRI.

【Keywords】 Programmed cell death;Myocardial ischemia-reperfusion injury;Mechanism

在世界范围内，心血管疾病是最常见的非传染性疾病，约占全球死亡人数的1/3，给全世界造成了严重的社会和健康压力[1]。（剩余11362字）