鱼精蛋白在心脏外科和介入手术中的应用进展

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Application of Protamine in Cardiac Surgery and Interventional Procedures

BAI Jiaqi1，ZHANG Chuang1，CHEN Haiwei1，XU Hongbo 2 ，WANG Qi1 （1.Departmentof Cardiology，The Sixth Medical Centerof ChinesePLA General Hospital，Beijing1Oo048，China; 2. Sanitary Company，Logistics Support Battalion，Troop 66O28，Chengde O6700o，Hebei ，China）

【Abstract】Optimizinganticoagulationmanagementduringtheprioperativepriodofcardiacsurgeryiscrucialforensuringsurgical safetyHepaictcoalantsideledigretsiltitoalatidotae antagonist，canapidlyreversetheaticoagulantfctandrestorecoaguationfunctionthoughachargeeutralizationmchanismCut chalengesmainldutdialaofaeaglcofdaadddiila diferentinterventionalproceduresispaperexploresthediferentialuseofprotamineincardiacsurgeryndcardiacinterentionand proposesuggestosforfutureearchirectiosrovdingtoicalbasisndpracticalgdancetotiizenticoaglatioagt in the perioperative period of cardiac surgery，with the aim of enhancing surgical safetyand improving patient outcomes.

【Keywords】 Heparin;Protamine;Cardiac Surgery;Cardiac Intervention

心脏手术是治疗心血管疾病的重要方法之一，有效的抗凝管理以及精准的抗凝逆转是保障手术顺利实施、减少术后并发症的关键环节。（剩余12562字）