生物信息学在我国医学研究生学位论文中的应用现状：基于VOSviewer的文献计量分析

打开文本图片集

【中图分类号】G353.1；R73 【文献标识码】A

【Abstract】 Objective To analyze the application status of bioinformatics on Chinese medical graduate students.Methods Available academic thesis was filtered with a topic of bioinformatics medical research ranging from 2003 January 1st to 2023 December 31st in CNKI and WanFang Database. The VOSviewer software was used to analyze the research hotspots of the academic thesis of Chinese medical graduate students，taking oncology as an example， the application status of bioinformatics in clinical practice was investigated. Results A total of 22，298 theseswere included，comprising14，036 master'stheses （62.95%） and8，262doctoral theses （37.05% ） In the last two decades，the number of bioinformatics-related thesis for Chinese medical student has been increasing continuously. The research hotspots of academic thesis mainly focused on expression analysis， mechanistic study， database and oncology. Notably， oncology-related research accounted for 45.72% of the theses. For lung cancer， application of bioinformatics has provided data support for pharmacological target investigation， diagnosis assstance and therapeutic effect monitoring in preclinical research.In addition， bioinformatics has been employed to aid clinical decision making， such as diagnosis and determination of therapeutic strategies. Conclusion The application of bioinformatics in the theses of medical postgraduates in China is increasing rapidly，particularly in the field of oncology. In clinical oncology practice，bioinformatics plays a pivotal role in early diagnosis，personalized therapy，and prognostic evaluation.

【Keywords】Bioinformatics; Oncology; Medicine; Graduate student; Bibliometrics

生物信息学是随人类基因组计划启动而兴起的一门学科，其基于高通量分析手段可将大量生物数据转化为有效信息，基于大数据的生物信息学分析已在生命科学领域尤其是医学领域得到广泛应用。（剩余7813字）