饮食质量与肌少症性肥胖的关联研究：基于NHANES数据库

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【关键词】饮食质量；肌少症性肥胖；健康饮食指数；中介分析【中图分类号】 ； R589.2 【文献标识码】A

【Abstract】 Objective To explore the association between dietary quality and sarcopenic obesity （SO）. Methods Based on data from the National Health and Nutrition Examination Survey（NHANES） in the United States from 2011 to 2018， participants in four survey cycles were selected as the study subjects.Weighted multivariate Logistic regression analysis was used to explore the association and interaction between Healthy Eating Index 2020（HEI-2020）and SO，and the mediating effects of inflammation， metabolism，and nutritional status on the relationship between HEI-2020 and SO were analyzed. ResultsA total of 8，602 participants were included，of whom 504 had SO， with a weighted prevalence ofapproximately 5.33% ，The SO group had lower HEI-2020 scores.Multivariate Logistic regression analysis showed that，after adjusting forage，sex，lifestyle，related comorbidities，and energy intake，compared with low HEI-2020 scores， medium HEI-2020 scores [OR .=0.73 ， 95%CI （0.54，0.99）] and high HEI-2020 scores [OR .=0.50 ， 95%CI （0.35， 0.72）] were negatively correlated with SO. Subgroup analysis showed that， except for low-income groups and those with sedentary time ≥8 hours，high HEI-2020 scores were negatively correlated with SO. No interaction was found between age，sex，education level，income level，or sedentary time on the association between HEI-2020 and SO.Mediation analysis showed that systemic inflammatory response index （SIRI）， glycated hemoglobin，non-HDL cholesterol to HDL cholesterol ratio （NHHR），albumin，and plasma vitamin D negatively mediated the relationship between HEI-2020 and SO.Conclusion Dietary quality is negatively correlated with SO.HEI-2020 can affect SO through the mediating effects of SIRI， glycated hemoglobin， NHHR，albumin， and plasma vitamin D. We should strengthen dietary health education， improve the dietary quality of residents，and promote healthy aging.

【Keywords】Dietary quality; Sarcopenic obesity; Healthy eating index; Mediation analysis

肌少症性肥胖（sarcopenicobesity，SO）是一种肌肉减少症和肥胖同时存在的疾病状态，临床表现为肌肉质量衰减伴肌肉功能减退和体内脂肪过度堆积并存[。（剩余18145字）