芪归八味汤对ACS合并T2DM病人PCI术后心功能及氧化应激指标的影响

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AbstractObjective:Toexplore theefectsQiguiBazhengDecoctiononcardiacfunctionandoxidativestressindicators inpatientswith acutecoronarysyndrome(AC)omplicatedwittype2diabetesmelitusD)afterpercutaneousoronaryintervention(Cethods: Atotal 102 patients with ACSandT2DMwho underwentPCItreatment wererandomlydivided intoresearch groupandthecontrol group,with51casesineachgroupaccordingtotherandomnumbertablemethod.controlgrouppatientsweregivenconventional Westermedicinetreatment,hiletheresearchgrouppatientsweretreatedwithQjuuiBaoweiDecoctioninaddiontothtreatment thecontrolgop.acydactideiisdedddtsd the two groups.Results: overall clinical effective rate the research group was 96.08% ,whichwas higher than that the control group (78.43%) ,thedifferencewasstatisticallysignificant( P<0.05) .Aftertreatment,the leftventricularejection fraction(LVEF) in both groupsincreasedcomparedtothatbeforetreatment,hiletheleftventricularend-diastolicdiameterLVEDD)andleftventricularndsystolicdiameterLVESD)decreasedomparedtotatbeforetreatmentmoreover,theLVEFintheresearchgroupwashigherthanthat in the control group,and the LVEDD and LVESD were lower than those in the control group( .Aftertreatment,the levels glutathioneperoxidase(GSH-Px)andsuperoxiddismutase(SOD)inbothgroupsincreasedcomparedtobeforetreatmenthilethelevel malondialdehyde(MDA) decreased compared to that before treatment, moreover,the GSH Px and SOD levels in the research group were higher than those in thecontrol group,andthe MDA level was lower than thatinthecontrol group( P<0.05) .comparisonthe total incidence rates adverse events in the two groupsshowed no statistically significant diference( P>0.05) .Conclusion:Qigui Baowei Decoctioncanimprovethecardiacfunctionandoxidativestress levelsACSpatientswithTDMwhoundergoPClwithbeteefficacy.
Keywordsacutecoronary syndrome;type2 diabetes; Qigui Bawei Decoction; heart function; oxidative stress
随着我国人民的生活习惯以及经济水平的变化,加之社会老龄化的加剧,发生心血管病变的人数日益增加。(剩余6703字)