高效生物胺降解菌酿酒酵母Ｚ5的降胺机制

打开文本图片集

Mechanism of Biogenic Amine Degradation by a Highly Efficient Biogenic Amine-Degrading Strain， Saccharomyces cerevisiae Z5

FANRong，CHENLi，WANGLi，TANXu， JIANG Ziyi，LI Ke，WANGYuanliang* （CollegeofFoodScience and Technology，HunanAgricultural University，Changsha ，China）

Abstract：The mechanism of biogenic amine degradation by the Saccharomyces cerevisiae wild-type strain Hl and the mutant strain Z5 and related metabolic pathways were explored through transcriptomic and metabolomic analyses.It was foundthat polyamineoxidaseencoded bytheFMS1gene playedacrucialrole indegrading biogenicamines，particularly spermidine and spermine.Under amine stressthe mutant strain Z5 enhanced its degradation eficiency for biogenic amines by regulating polyamine metabolic pathways.Additionally， the glutathione metabolism pathway was found to play an important role inthe amine degradation process of strain Z5.Its polyamine oxidase activity under amine stress was significantly higher than that of thewild-type strain Hl （P<0.05） ！

Keywords：biogenic amines; Saccharomyces cerevisiae;omics analysis; polyamine oxidase;degradation mechanism

DOI：10.7506/rlyj1001-8123-20250411-107

中图分类号：TS251.1 文献标志码：A 文章编号：1001-8123（2026）03-0017-09

引文格式：

樊蓉，陈力，王丽，等．高效生物胺降解菌酿酒酵母Z5的降胺机制[J].肉类研究，2026，40（3）：17-25.DOI：10.7506/

rlyj1001-8123-20250411-107. http：//www.rlyj.net.cn

FANRong，CHENLiWANGLi，etal.Mechanismof biogenic amine degradationbyahighlyefficientbiogenicamine

degrading strain，Saccharomycescerevisiae Z5[J].MeatResearch，2026，40（3）：17-25.DOI：10.7506/rlyj1001-8123-

20250411-107.http：//www.rlyj.net.cn

生物胺是一类低分子质量含氮有机化合物，主要由氨基酸通过微生物脱羧作用生成，广泛存在于发酵食品中。（剩余16794字）